Department of Psychiatry, Xiamen Xianyue Hospital, Xiamen, China.
Unit of Psychiatry, Department of Public Health and Medicinal Administration, & Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao SAR, China.
Transl Psychiatry. 2022 Jul 29;12(1):303. doi: 10.1038/s41398-022-02045-2.
The coronavirus disease 2019 (COVID-19) pandemic has a disproportionate impact on vulnerable subpopulations, including those with severe mental illness (SMI). This study examined the one-year prevalence of suicidal ideation (SI), suicide plans (SP), and suicide attempts (SA) in bipolar disorder (BD) and schizophrenia (SCZ) patients during the pandemic. Prevalence rates were compared between the two disorders and associated factors were examined. A survey was conducted in six tertiary psychiatric hospitals and psychiatric units. People with a diagnosis of BD or SCZ were invited to participate. SI, SP, and SA (suicidality for short) were assessed and associated factors were examined using binary logistical regression. The 1-year prevalence of SI, SP and SA in BD patients were 58.3%, (95% CI: 54.1-62.6%), 38.4% (95% CI: 34.3-42.6%) and 38.6% (95% CI: 34.5-42.8%), respectively, which were higher than the corresponding figures in SCZ patients (SI: 33.2%, 95% CI: 28.6-37.8%; SP: 16.8%, 95% CI: 13.2-20.5%; SA: 19.4%, 95% CI: 15.5-23.3%). Patients with younger age, experience of cyberbullying, a history of SA among family or friends, a higher fatigue and physical pain score, inpatient status, and severe depressive symptoms were more likely to have suicidality. The COVID-19 pandemic was associated with increased risk of suicidality, particularly in BD patients. It is of importance to regularly screen suicidality in BD and SCZ patients during the pandemic even if they are clinically stable.
新型冠状病毒肺炎(COVID-19)大流行对弱势群体产生了不成比例的影响,包括患有严重精神疾病(SMI)的人群。本研究旨在调查 COVID-19 大流行期间双相情感障碍(BD)和精神分裂症(SCZ)患者自杀意念(SI)、自杀计划(SP)和自杀企图(SA)的一年患病率,并比较两种疾病之间的患病率差异,同时探讨相关的影响因素。该研究采用问卷调查的方式,在六所三级精神病医院和精神科病房进行。邀请被诊断为 BD 或 SCZ 的患者参与。采用二元逻辑回归分析评估 SI、SP 和 SA(简称为自杀)及其相关因素。BD 患者的 SI、SP 和 SA 的一年患病率分别为 58.3%(95%CI:54.1-62.6%)、38.4%(95%CI:34.3-42.6%)和 38.6%(95%CI:34.5-42.8%),均高于 SCZ 患者(SI:33.2%,95%CI:28.6-37.8%;SP:16.8%,95%CI:13.2-20.5%;SA:19.4%,95%CI:15.5-23.3%)。年龄较小、经历网络欺凌、家族或朋友中有自杀史、疲劳和身体疼痛评分较高、住院和严重抑郁症状的患者更有可能出现自杀意念。COVID-19 大流行与自杀风险增加相关,尤其是在 BD 患者中。即使在临床稳定的情况下,在大流行期间对 BD 和 SCZ 患者定期筛查自杀意念也非常重要。