Borets V M, Lis M A, Pyrochkin V M, Kishkovich V P, Butkevich N D
Vopr Pitan. 1987 Mar-Apr(2):15-7.
The therapeutic effectiveness of the pantothenic acid drugs: calciipantothenas and pantethine, was studied in 182 patients with coronary heart disease and stable angina of effort. It is shown that both the drugs produce favourable effects on certain parameters of hemodynamics, on the metabolism of lipids, riboflavin and ascorbic acid. It is recommended that the administration of calciipantothenas in a dose of 300 mg/day, during 3 weeks, be included into the combined treatment of coronary patients with no manifest disorders of lipid metabolism. Patients with manifest hyperlipidemia should be administered pantethine in a dose of 500 mg/day.
对182例冠心病稳定型劳累性心绞痛患者研究了泛酸药物（泛酸钙和泛癸利酮）的治疗效果。结果表明，这两种药物对血流动力学的某些参数、脂质、核黄素和抗坏血酸的代谢均产生有益影响。建议对于脂质代谢无明显紊乱的冠心病患者，在联合治疗中纳入剂量为300毫克/天的泛酸钙，疗程3周。对于明显高脂血症患者，应给予剂量为500毫克/天的泛癸利酮。
