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口腔黏膜坏死—被忽视的疾病:预防胜于治疗。

Noma, a neglected disease: prevention is better than cure.

机构信息

Nudibrink Research Consultancy, Cape Town, South Africa.

Centre for Applied Human Rights, University of York, York, United Kingdom.

出版信息

Curr Opin Otolaryngol Head Neck Surg. 2022 Aug 1;30(4):219-225. doi: 10.1097/MOO.0000000000000819. Epub 2022 Jul 5.

Abstract

PURPOSE OF REVIEW

There is a need for concerted effort to increase Global awareness about noma (cancrum oris). This paper aims to summarize the recent literature on noma and provide suggestions that could be implemented to raise awareness about this neglected disease.

RECENT FINDINGS

Noma has been recognized, diagnosed and reported for centuries. Despite significant progress in scientific methods over time, the published literature on noma has predominantly been of low level clinical and scientific evidence. Recent studies have reported on noma's global distribution and its predisposing risk factors, its treatment, its knowledge and beliefs and has included a number of literature reviews. Noma cases are being reported from an increasingly diverse set of geographical locations.

SUMMARY

Noma has largely been neglected in the research sphere. Noma is a preventable disease and its progression can be halted if patients are recognized and treated in the early stages of disease. Treatment for late stage noma survivors remains complex and time consuming, requiring substantial human and financial resources most commonly not achieving functional and cosmetic anatomy. The ultimate aim is therefore prevention, initiatives should be integrated into existing health programs.

摘要

目的综述

有必要共同努力提高全球对口疮(坏疽性口炎)的认识。本文旨在总结近期关于口蹄疫的文献,并提出可能有助于提高对口蹄疫这一被忽视疾病认识的建议。

最新发现

几个世纪以来,人们对口疮的认识、诊断和报告一直在进行。尽管随着时间的推移,科学方法取得了重大进展,但关于口蹄疫的已发表文献主要是低水平的临床和科学证据。最近的研究报告了口蹄疫的全球分布及其易患风险因素、治疗方法、对口蹄疫的认识和信念,并包括了一些文献综述。来自越来越多不同地理位置的报告都有口蹄疫病例。

总结

口蹄疫在研究领域基本上被忽视了。口蹄疫是一种可预防的疾病,如果患者在疾病的早期阶段得到识别和治疗,其进展是可以停止的。对口疮晚期幸存者的治疗仍然很复杂,需要大量的人力和财力,而且通常无法实现功能和美容解剖。因此,最终目标是预防,应将这些举措纳入现有的卫生计划中。

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