Ecological Security and Protection Key Laboratory of Sichuan Province, College of Resources and Environmental Engineering, Mianyang Normal University, 621000, Mianyang, China.
Key Laboratory of Chemical Synthesis and Pollution Control of Sichuan Province, School of Chemistry and Chemical Engineering, China West Normal University, 637002, Nanchong, China.
J Fluoresc. 2022 Nov;32(6):2077-2086. doi: 10.1007/s10895-022-02966-7. Epub 2022 Jul 30.
The development of mercury ion selective fluorescent probe is significant because it is one of toxic heavy metals and poses great risks and hazards to human health. Herein, we develop a mercury ion-selective fluorescent probe, namely IB, based on imidazole decorated benzothiadiazole that obtained by a facile palladium catalytic C-N coupling reaction. IB exhibits high selectivity and sensitivity towards mercury ion in water with nearly 32-fold fluorescent enhancement. The detection limit is calculated to be 0.93 nmol/L. In addition, the sensing of mercury ion can be conducted in a wide pH scope ranging from 4.0 to 10.0. Subsequently, the mercury ion elicits fluorescence of IB solution can be quenched by the addition of cyanide anions, showing "off-on-off" fluorescence transformation with at least 5 cycles, demonstrating the reversible sensing ability of IB. Furthermore, an INHIBIT logical detector has been developed using mercury ion and cyanide anions as inputs and fluorescence of IB as output. Significantly, IB can be utilized for mercury ion detection in real water sample.
汞离子选择性荧光探针的开发具有重要意义，因为汞是一种有毒重金属，对人类健康构成极大的风险和危害。在此，我们开发了一种基于咪唑修饰的苯并噻二唑的汞离子选择性荧光探针 IB，该探针通过简便的钯催化 C-N 偶联反应获得。IB 在水中对汞离子具有高选择性和灵敏度，荧光增强近 32 倍。检测限计算为 0.93 nmol/L。此外，传感汞离子的 pH 值范围从 4.0 到 10.0 很宽。随后，加入氰根阴离子可以使 IB 溶液的汞离子引发的荧光猝灭，表现出至少 5 个循环的“关-开-关”荧光转变，证明了 IB 的可逆传感能力。此外，还开发了一种使用汞离子和氰根阴离子作为输入以及 IB 的荧光作为输出的 INHIBIT 逻辑探测器。重要的是，IB 可用于实际水样中的汞离子检测。
