Ott A
Z Hautkr. 1987 Mar 1;62(5):369-70, 375-8.
We report on a 72-year-old man suffering from transient acantholytic dermatosis (TAD). The histologic pattern resembled that of Darier's disease. The disorder first set on after an episode of intensive exposure to sunlight and persisted for 6 years. The only drug the patient took during this period was the prophylactic antimaterial preparation, Fansidar. His sensitivity to UVB radiation was markedly increased. After Fansidar was replaced by Resochin, the skin cleared up. After one year the sensitivity to UVB had normalized.
我们报告了一例患有暂时性棘层松解性皮病(TAD)的72岁男性患者。组织学表现类似于毛囊角化病。该疾病在一次强烈日晒后首次发作,并持续了6年。在此期间患者唯一服用的药物是预防性抗疟药复方磺胺多辛。他对中波紫外线(UVB)辐射的敏感性显著增加。在将复方磺胺多辛换成氯喹后,皮肤症状消退。一年后,对UVB的敏感性恢复正常。