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非编码 RNA 调控鹿茸组织生长发育的研究进展。

Progress of Noncoding RNA Regulating the Growth and Development of Antler Tissue Research.

机构信息

Biochemistry and Molecular Biology, Jilin Agricultural University, Changchun City, Jilin Province 130000, China.

出版信息

Biomed Res Int. 2022 Jul 19;2022:3541577. doi: 10.1155/2022/3541577. eCollection 2022.

Abstract

Antler is the secondary sexual characteristic of deer, which develops on the forehead at puberty. It is the only organ that can be regenerated entirely in mammals. Therefore, it is often used as a research model in the field of organ regeneration and wound repair. Many growth factors and proteins play an active role throughout the developmental process of antler regeneration. With the rapid development of sequencing technology, more and more noncoding RNAs (ncRNAs) have been discovered, and the relationship between ncRNA and antler regeneration has gradually become clear. This paper focuses on the research progress of several ncRNAs (including miRNA and lncRNA) in deer antler tissues, which are helpful to reveal the molecular mechanism of deer antler regeneration at the molecular level.

摘要

鹿茸是鹿的第二性征,在青春期时发育于额头上。它是哺乳动物中唯一能够完全再生的器官。因此,它常被用作器官再生和伤口修复领域的研究模型。许多生长因子和蛋白质在鹿茸再生的整个发育过程中发挥着积极的作用。随着测序技术的飞速发展,越来越多的非编码 RNA(ncRNA)被发现,ncRNA 与鹿茸再生的关系逐渐明朗。本文主要关注几种 ncRNA(包括 miRNA 和 lncRNA)在鹿鹿茸组织中的研究进展,有助于从分子水平揭示鹿鹿茸再生的分子机制。

相似文献

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Deer antler--a novel model for studying organ regeneration in mammals.鹿茸——一种研究哺乳动物器官再生的新型模型。
Int J Biochem Cell Biol. 2014 Nov;56:111-22. doi: 10.1016/j.biocel.2014.07.007. Epub 2014 Jul 18.
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Morphogenetic aspects of deer antler development.鹿茸发育的形态发生学方面
Front Biosci (Elite Ed). 2012 Jan 1;4(5):1836-42. doi: 10.2741/505.

本文引用的文献

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The role of microRNA in nutritional control.miRNA 在营养控制中的作用。
J Intern Med. 2015 Aug;278(2):99-109. doi: 10.1111/joim.12372. Epub 2015 May 19.

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