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工作犬的中毒综合征

Toxidromes for Working Dogs.

作者信息

McMichael Maureen A, Singletary Melissa, Akingbemi Benson T

机构信息

Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.

Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.

出版信息

Front Vet Sci. 2022 Jul 15;9:898100. doi: 10.3389/fvets.2022.898100. eCollection 2022.

Abstract

Terrorist attacks with biological and chemical warfare agents are increasing in frequency worldwide. Additionally, hazardous chemical accidents, illicit drug laboratories and intentional poisonings are potential sites for exposure to working dogs. Working dogs play a crucial role in law enforcement, military and search and rescue teams. Their intelligence, agility and strength make them ideal partners to be deployed to these natural disaster sites, terrorist attacks and industrial accidents. This, unfortunately, leads to increasing exposure to chemical and biological weapons and other hazardous substances. First responders have little to no training in emergency care of working dogs and veterinarians have very little training on recognition of the clinical signs of many of these agents. In order to ensure a rapid medical response at the scene first responders and veterinarians need a primer on these agents. Identifying a specific agent amidst the chaos of a mass casualty event is challenging. Toxidromes are a constellation of clinical and/or laboratory findings that allow for rapid identification of the clinical signs associated with a class of toxin and have been helpful in human medical triage. Focusing on a class of agents rather than on each individual toxin, allows for more expedient administration of antidotes and appropriate supportive care. This article reviews toxidromes for the most common chemical weapons with a special emphasis on clinical signs that are specific (and different) for canines as well as appropriate antidotes for working canines. To our knowledge, there are no publications describing toxidromes for working dogs.

摘要

全球范围内,使用生物和化学战剂的恐怖袭击事件愈发频繁。此外,危险化学品事故、非法毒品实验室及蓄意投毒事件都是工作犬可能接触有害物质的潜在场所。工作犬在执法、军事及搜救队伍中发挥着关键作用。它们的智慧、敏捷性和力量使其成为被部署到这些自然灾害现场、恐怖袭击现场及工业事故现场的理想伙伴。不幸的是,这导致它们接触化学和生物武器及其他有害物质的情况日益增多。急救人员在工作犬急救方面几乎没有接受过培训,而兽医对许多此类战剂临床症状的识别培训也非常少。为确保在现场能迅速进行医疗救治,急救人员和兽医需要了解这些战剂的基本知识。在大规模伤亡事件的混乱局面中识别特定战剂颇具挑战性。中毒综合征是一系列临床和/或实验室检查结果,可据此快速识别与一类毒素相关的临床症状,对人类医疗分诊很有帮助。关注一类战剂而非每种单独的毒素,有助于更迅速地施用解毒剂并提供适当的支持性护理。本文回顾了最常见化学武器的中毒综合征,特别强调了犬类特有的(且不同的)临床症状以及工作犬适用的解毒剂。据我们所知,尚无关于工作犬中毒综合征的相关出版物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d18/9334742/84f2c2521d25/fvets-09-898100-g0001.jpg

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