Suwal Amar, Shrestha Biraj, Paudel Anish, Paudel Rubina, Basnet Sijan
Internal medicine, Reading Hospital-Tower Health, Reading, USA.
Internal Medicine, Reading Hospital-Tower Health, Reading, USA.
Cureus. 2022 Jun 27;14(6):e26375. doi: 10.7759/cureus.26375. eCollection 2022 Jun.
Macrophage activation syndrome (MAS) is a potentially fatal complication of an autoimmune rheumatologic disease characterized by overwhelming inflammation, multiorgan failure, and high mortality if untreated. We report a rare case of a 56-year-old man who presented with fever for three weeks and had a constellation of clinical features and laboratory findings, meeting the diagnostic criteria for systemic lupus erythematosus (SLE) and SLE-associated MAS. He was treated with high dose intravenous corticosteroid and hydroxychloroquine, resulting in resolution of fever and dramatic clinical improvement.
巨噬细胞活化综合征（MAS）是自身免疫性风湿性疾病的一种潜在致命并发症，其特征为炎症反应剧烈、多器官功能衰竭，若不治疗死亡率很高。我们报告一例罕见病例，一名56岁男性，发热三周，具有一系列临床特征和实验室检查结果，符合系统性红斑狼疮（SLE）及SLE相关MAS的诊断标准。他接受了大剂量静脉注射皮质类固醇和羟氯喹治疗，发热消退，临床症状显著改善。
