Orbán Gábor, Salló Zoltán, Perge Péter, Ábrahám Pál, Piros Katalin, Nagy Klaudia Vivien, Osztheimer István, Merkely Béla, Gellér László, Szegedi Nándor
Heart and Vascular Center, Semmelweis University, Budapest, Hungary.
Front Cardiovasc Med. 2022 Jul 13;9:941434. doi: 10.3389/fcvm.2022.941434. eCollection 2022.
Pulmonary vein isolation is the cornerstone of rhythm-control therapy for atrial fibrillation (AF). The very high-power, short-duration (vHPSD) radiofrequency (RF) ablation is a novel technology that favors resistive heating while decreasing the role of conductive heating. Our study aimed to evaluate the correlations between contact force (CF), power, impedance drop (ID), and temperature; and to assess their role in lesion formation with the vHPSD technique.
Consecutive patients who underwent initial point-by-point RF catheter ablation for AF were enrolled in the study. The vHPSD ablation was performed applying 90 W for 4 s with an 8 ml/min irrigation rate.
Data from 85 patients [median age 65 (59-71) years, 34% female] were collected. The median procedure time, left atrial dwelling time, and fluoroscopy time were 70 (60-90) min, 49 (42-58) min, and 7 (5-11) min, respectively. The median RF time was 312 (237-365) sec. No steam pop nor major complications occurred. A total of 6,551 vHPSD RF points were analyzed. The median of CF, maximum temperature, and ID were 14 (10-21) g, 47.6 (45.1-50.4) °C, and 8 (6-10) Ohms, respectively. CF correlated significantly with the maximum temperature ( < 0.0001). A CF of 5 g and above was associated with a significantly higher temperature compared to those lesions with a CF below 5 grams ( < 0.0001). Bilateral first-pass isolation rate was 84%. The 6-month AF-recurrence rate was 7%.
The maximum temperature and CF significantly correlate with each other during vHPSD applications. A CF ≥ 5 g leads to better tissue heating and thus might be more likely to result in good lesion formation, although this clinical study was unable to assess actual lesion sizes.
肺静脉隔离是房颤(AF)节律控制治疗的基石。超高功率、短持续时间(vHPSD)射频(RF)消融是一项新技术,有利于电阻性加热,同时减少传导性加热的作用。我们的研究旨在评估接触力(CF)、功率、阻抗下降(ID)和温度之间的相关性;并评估它们在vHPSD技术形成损伤中的作用。
连续纳入接受首次逐点RF导管消融治疗房颤的患者。vHPSD消融以90W功率、8ml/min的灌注速率持续4秒进行。
收集了85例患者的数据[中位年龄65(59 - 71)岁,34%为女性]。中位手术时间、左心房停留时间和透视时间分别为70(60 - 90)分钟、49(42 - 58)分钟和7(5 - 11)分钟。中位RF时间为312(237 - 365)秒。未发生蒸汽泡形成或重大并发症。共分析了6551个vHPSD RF点。CF、最高温度和ID的中位数分别为14(10 - 21)克、47.6(45.1 - 50.4)℃和8(6 - 10)欧姆。CF与最高温度显著相关(<0.0001)。与CF低于5克的损伤相比,CF为5克及以上的损伤温度显著更高(<0.0001)。双侧首次通过隔离率为84%。6个月房颤复发率为7%。
在vHPSD应用过程中,最高温度和CF彼此显著相关。CF≥5克可导致更好的组织加热,因此可能更有可能导致良好的损伤形成,尽管这项临床研究无法评估实际损伤大小。