Si Ying, Sun Bo, Zhao Ting, Xiao Ke, Zhao Dong-Xia, Huang Yong-Mao
Department of Infectious Diseases, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Department of Ultrasound, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Front Oncol. 2022 Jul 13;12:873338. doi: 10.3389/fonc.2022.873338. eCollection 2022.
Focal nodular hyperplasia (FNH) of the liver is a benign lesion characterized by hypertrophic nodules with central star-shaped fibrous scars. The etiology and pathogenesis of FNH are not completely understood. A 43-year-old man was hospitalized because of acute abdominal pain. Emergency computed tomography(CT) showed hepatic tumor rupture and bleeding. The patient's condition improved following arteriographic embolization to stop bleeding. Laparotomy confirmed spontaneous rupture and hemorrhage of focal hyperplasia and the patient remains asymptomatic after an uneventful recovery. FNH with spontaneous rupture and bleeding is extremely rare. Currently, there is no unified management standard for FNH and most previous studies recommend observation and follow-up. We recommend consideration of surgical treatment of cases with spontaneous rupture and bleeding.
肝脏局灶性结节性增生(FNH)是一种良性病变,其特征为具有中央星形纤维瘢痕的肥大结节。FNH的病因和发病机制尚未完全明确。一名43岁男性因急性腹痛入院。急诊计算机断层扫描(CT)显示肝肿瘤破裂出血。经动脉造影栓塞止血后,患者病情好转。剖腹手术证实为局灶性增生自发破裂出血,患者恢复顺利,术后无症状。FNH自发破裂出血极为罕见。目前,对于FNH尚无统一的治疗标准,大多数既往研究建议观察和随访。我们建议对自发破裂出血的病例考虑手术治疗。