Department of Pathology and Laboratory Medicine, Albany Medical Center, Albany, NY, USA.
Int J Surg Pathol. 2023 Aug;31(5):509-520. doi: 10.1177/10668969221108517. Epub 2022 Aug 1.
rearranged Renal cell carcinoma (RCC) is not very common, and demonstrates unique heterogenous morphological features overlapping other recognized entities and distinct immunoprofile. It can be seen in any age group, therefore practicing pathologists should be aware of the distinctive clinical settings and histologic findings associated with these tumors and subsequently employ an adequate panel of ancillary studies in order to confirm the diagnosis. Recognizing these entities remains crucial for future clinical trials and development of novel therapies.
重排肾细胞癌（RCC）并不常见，表现出独特的异质性形态特征，与其他已识别的实体重叠，并具有独特的免疫表型。它可见于任何年龄组，因此，临床病理医生应该了解与这些肿瘤相关的独特临床背景和组织学发现，并随后采用适当的辅助研究来确认诊断。识别这些实体对于未来的临床试验和新型治疗方法的开发仍然至关重要。
