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北美牦牛(Bos grunniens)的色素沉着表型与耳聋相关。

Deafness associated with pigmentation phenotypes in North American yaks (Bos grunniens).

机构信息

Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA.

US Yaks, Chadron, NE.

出版信息

Am J Vet Res. 2022 Aug 3;83(10):ajvr.22.03.0050. doi: 10.2460/ajvr.22.03.0050.

DOI:10.2460/ajvr.22.03.0050
Abstract

OBJECTIVE

To assess the presence of suspected pigment-associated deafness in North American yaks (Bos grunniens).

ANIMALS

12 North American yaks, including 11 with the homozygous piebald Royal pigmentation phenotype and 1 with the heterozygous piebald Trim phenotype.

PROCEDURES

Hearing was assessed using the brainstem auditory evoked response (BAER) on yaks restrained in the head gate of a grooming chute.

RESULTS

Five of the Royal yaks and the Trim yak had hearing in both ears. Six Royal yaks were affected; 3 were deaf in 1 ear and 3 were deaf in both ears.

CLINICAL RELEVANCE

For the first time, probable sensorineural deafness has been confirmed to be present in Royal yaks. The disorder is assumed to be congenital and associated with white pigmentation, based on the pattern of occurrence in other species.

摘要

目的

评估北美牦牛(Bos grunniens)中疑似色素相关耳聋的存在情况。

动物

12 头北美牦牛,包括 11 头纯合花斑 Royal 色素表型和 1 头杂合花斑 Trim 表型。

程序

通过将牦牛束缚在梳理槽的头部门中,使用脑干听觉诱发电位(BAER)评估听力。

结果

5 头 Royal 牦牛和 1 头 Trim 牦牛双耳均有听力。6 头 Royal 牦牛受到影响;3 头在 1 耳失聪,3 头在双耳失聪。

临床相关性

首次证实 Royal 牦牛存在可能的感觉神经性耳聋。根据其他物种的发病模式,假设该疾病是先天性的,并与白色色素沉着有关。

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