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老年人股骨上端骨折的外科治疗中延迟负重是否会导致更多并发症?一项前瞻性研究。

Does delayed weight bearing in the surgical management of fractures of the upper end of the femur in the elderly lead to more complications? A prospective study.

机构信息

Service de chirurgie orthopédique et traumatologique, hôpital Cochin, Assistance Publique - hôpitaux de Paris, Paris, France; Université de Paris, faculté de médecine Paris-Centre, 75006 Paris, France.

Service de chirurgie orthopédique et traumatologique, hôpital Cochin, Assistance Publique - hôpitaux de Paris, Paris, France.

出版信息

Orthop Traumatol Surg Res. 2022 Nov;108(7):103381. doi: 10.1016/j.otsr.2022.103381. Epub 2022 Jul 29.

Abstract

INTRODUCTION

Fractures of the upper end of the femur (FUEF) lead to increased mortality and dependence in the elderly. However, mechanical complications after surgery persist in up to 20% of cases, which may justify a delayed resumption of full weight bearing to protect the osteosynthesis during consolidation.

HYPOTHESIS

Our hypothesis was that the late resumption of weight bearing in an elderly population after a FUEF would be limited by a higher frequency of medical complications.

METHODS

This was a prospective monocentric study including patients aged 80 or over with an isolated FUEF requiring osteosynthesis. The operator decided on the discharge. The primary endpoint was to show a difference in a medical complication score created for this study (APRETAR), between a group with, and a group without, weight bearing delayed by 45 days.

RESULTS

Between 2016 and 2019, 254 patients (88±5.6 years, 77.6% women) were included, and of these, 70 (27.6%) had delayed weight bearing. The mean APRETAR at 45 days was greater in the delayed weight bearing group (5.9±8.6 vs. 5.7±11.0; p<0.001). One-year mortality was 12.6% (32 patients), with no difference between the two groups (p=0.51). The level of dependence was significant (IADL at 2.2±1.7), with some comorbidities (Charlson at 2.9±2.2 and CIRS-G at 6.5±4.3) and all comparable across the two groups but with low cognitive levels, especially in the group with delayed weight bearing (MMSE 15.9±10.7 vs. 21±6.9; p<0.001).

CONCLUSION

This prospective study shows that delaying weight bearing in the elderly population, even for mechanical problems with FUEF, statistically increases medical complications but in a clinically acceptable manner.

LEVEL OF EVIDENCE

II, Prospective cohort study.

摘要

引言

股骨上端骨折(FUEF)会导致老年人死亡率和依赖性增加。然而,手术后的机械并发症在多达 20%的病例中仍然存在,这可能证明在巩固过程中为了保护内固定需要延迟完全负重。

假设

我们的假设是,在 FUEF 后,老年人群体延迟负重会因更高频率的医疗并发症而受到限制。

方法

这是一项前瞻性单中心研究,包括需要内固定治疗的 80 岁及以上的孤立性 FUEF 患者。由术者决定出院。主要终点是在为这项研究创建的一个医疗并发症评分(APRETAR)中,比较负重延迟 45 天的患者组和无负重延迟的患者组之间的差异。

结果

2016 年至 2019 年期间,共纳入 254 名患者(88±5.6 岁,77.6%为女性),其中 70 名(27.6%)延迟负重。延迟负重组在第 45 天的平均 APRETAR 更高(5.9±8.6 比 5.7±11.0;p<0.001)。一年死亡率为 12.6%(32 名患者),两组间无差异(p=0.51)。依赖性程度显著(IADL 为 2.2±1.7),存在一些合并症(Charlson 为 2.9±2.2,CIRS-G 为 6.5±4.3),所有这些在两组间均可比,但认知水平较低,尤其是在延迟负重组(MMSE 为 15.9±10.7 比 21±6.9;p<0.001)。

结论

这项前瞻性研究表明,即使是股骨上端骨折的机械问题,在老年人群体中延迟负重也会在统计学上增加医疗并发症,但在可接受的临床范围内。

证据水平

II 级,前瞻性队列研究。

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