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急性敌稗中毒的一种新治疗方法：病例报告

A New Treatment Approach for Acute Propanil Poisoning: A Case Report.

作者信息

Arunpriyandan Vaishnavi, Kt Sundaresan, Umakanth Maheswaran

机构信息

General Medicine, University Medical Unit, Teaching Hospital Batticaloa, Batticaloa, LKA.

Clinical Medicine, Faculty of Health Care Sciences, Teaching Hospital Batticaloa, Batticaloa, LKA.

出版信息

Cureus. 2022 Jun 29;14(6):e26416. doi: 10.7759/cureus.26416. eCollection 2022 Jun.

DOI:10.7759/cureus.26416
PMID:35915699
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9337783/
Abstract

Propanil is a widely used herbicide in agriculture and is also an important cause of poisoning in Sri Lanka. Incidence is around 2% and is commonly reported as self-poisoning. Although it is classified as an agent with low to medium toxicity, severe poisoning can cause lethal outcome and death especially when there is a limited medical facility. We describe a case of severe Propanil poisoning who was successfully treated in a peripheral hospital with available facilities.

摘要

敌稗是农业中广泛使用的除草剂，也是斯里兰卡中毒的一个重要原因。发病率约为2%，通常报告为自我中毒。尽管它被归类为低至中等毒性的制剂，但严重中毒可能导致致命后果甚至死亡，尤其是在医疗设施有限的情况下。我们描述了一例严重敌稗中毒病例，该病例在一家具备可用设施的基层医院成功得到治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c2f/9337783/085028b9a7df/cureus-0014-00000026416-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c2f/9337783/d0ff1ba38a19/cureus-0014-00000026416-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c2f/9337783/085028b9a7df/cureus-0014-00000026416-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c2f/9337783/d0ff1ba38a19/cureus-0014-00000026416-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c2f/9337783/085028b9a7df/cureus-0014-00000026416-i02.jpg

相似文献

1
A New Treatment Approach for Acute Propanil Poisoning: A Case Report.急性敌稗中毒的一种新治疗方法：病例报告
Cureus. 2022 Jun 29;14(6):e26416. doi: 10.7759/cureus.26416. eCollection 2022 Jun.
2
Exchange transfusion can be life-saving in severe propanil poisoning: a case report.换血疗法在严重敌稗中毒中可挽救生命：一例报告
BMC Res Notes. 2014 Oct 8;7:700. doi: 10.1186/1756-0500-7-700.
3
Clinical outcomes and kinetics of propanil following acute self-poisoning: a prospective case series.急性自服敌稗中毒后的临床结局及动力学：一项前瞻性病例系列研究
BMC Clin Pharmacol. 2009 Feb 16;9:3. doi: 10.1186/1472-6904-9-3.
4
A bedside test for methemoglobinemia, Sri Lanka.斯里兰卡高铁血红蛋白血症的床边检测
Bull World Health Organ. 2016 Aug 1;94(8):622-5. doi: 10.2471/BLT.15.158147. Epub 2016 Jun 14.
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A bedside test for methaemoglobinemia improved antidote use in propanil poisoning.一项用于检测高铁血红蛋白血症的床旁检测改善了敌稗中毒时解毒剂的使用情况。
Clin Toxicol (Phila). 2016 Aug;54(7):576-80. doi: 10.1080/15563650.2016.1177651. Epub 2016 May 19.
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Propanil poisoning.敌稗中毒
Ceylon Med J. 1997 Jun;42(2):81-4.
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Severe propanil [N-(3,4-dichlorophenyl) propanamide] pesticide self-poisoning.重度敌稗[N-(3,4-二氯苯基)丙酰胺]农药自服中毒。
J Toxicol Clin Toxicol. 2002;40(7):847-54. doi: 10.1081/clt-120016955.
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Clinical characteristics, treatment and outcomes of acute propanil poisoning in a 7-year retrospective cohort study.一项为期7年的回顾性队列研究中急性敌稗中毒的临床特征、治疗及转归
Toxicol Rep. 2022 May 4;9:1180-1188. doi: 10.1016/j.toxrep.2022.04.029. eCollection 2022.
9
Methemoglobin measurements are underestimated by the Radical 7 co-oximeter: experience from a series of moderate to severe propanil poisonings.经皮脉搏血氧饱和度仪对高铁血红蛋白的测量结果存在低估：来自一系列中度至重度敌稗中毒病例的经验。
Clin Toxicol (Phila). 2016 Nov;54(9):826-828. doi: 10.1080/15563650.2016.1217421. Epub 2016 Aug 23.
10
Pesticide poisoning initially suspected as a natural death.最初怀疑为自然死亡的农药中毒。
J Forensic Sci. 2001 Jan;46(1):165-70.

本文引用的文献

1
Clinical characteristics, treatment and outcomes of acute propanil poisoning in a 7-year retrospective cohort study.一项为期7年的回顾性队列研究中急性敌稗中毒的临床特征、治疗及转归
Toxicol Rep. 2022 May 4;9:1180-1188. doi: 10.1016/j.toxrep.2022.04.029. eCollection 2022.
2
Exchange transfusion can be life-saving in severe propanil poisoning: a case report.换血疗法在严重敌稗中毒中可挽救生命：一例报告
BMC Res Notes. 2014 Oct 8;7:700. doi: 10.1186/1756-0500-7-700.
3
Clinical outcomes and kinetics of propanil following acute self-poisoning: a prospective case series.
急性自服敌稗中毒后的临床结局及动力学：一项前瞻性病例系列研究
BMC Clin Pharmacol. 2009 Feb 16;9:3. doi: 10.1186/1472-6904-9-3.
4
Direct oxidant damage to red cells associated with propanil ingestion.与敌稗摄入相关的红细胞直接氧化损伤。
Ceylon Med J. 2003 Sep;48(3):88-9. doi: 10.4038/cmj.v48i3.3353.
5
Propanil poisoning.敌稗中毒
Ceylon Med J. 1997 Jun;42(2):81-4.
6
Metabolism of the arylamide herbicide propanil. I. Microsomal metabolism and in vitro methemoglobinemia.芳酰胺类除草剂敌稗的代谢。I. 微粒体代谢与体外高铁血红蛋白血症
Toxicol Appl Pharmacol. 1990 Mar 15;103(1):90-101. doi: 10.1016/0041-008x(90)90265-v.