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抽动秽语综合征及其他抽动障碍患者的睡眠障碍与睡眠问题:当前观点

Sleep Disorders and Sleep Problems in Patients With Tourette Syndrome and Other Tic Disorders: Current Perspectives.

作者信息

Jiménez-Jiménez Félix Javier, Alonso-Navarro Hortensia, García-Martín Elena, Agúndez José A G

机构信息

Section of Neurology, Hospital Universitario Del Sureste, Arganda del Rey, Madrid, Spain.

Universidad de Extremadura, University Institute of Molecular Pathology Biomarkers, ARADyAL, Cáceres, Spain.

出版信息

Nat Sci Sleep. 2022 Jul 25;14:1313-1331. doi: 10.2147/NSS.S340948. eCollection 2022.

Abstract

Sleep disorders seem to be a frequent complaint of patients diagnosed with Tourette syndrome (TS) or chronic or persistent tic disorders (CTD or PTD). In this review, we expanded a previously used search using 4 well-known databases up to February 15, 2022, looking for the coexistence of global and/or specific sleep disorders and polysomnographic studies performed on patients with TS/CTD/PTD. The references of interest in the topic were selected by hand. Sleep disorders in general, insomnia, different arousal disorders, the persistence of tics during sleep, excessive daytime sleepiness, and periodic limb movements during sleep (PLMS) were very frequent in patients with TS, most of them being more frequent in patients with comorbid Attention Deficit Hyperactivity Disorder. The most frequent results from polysomnographic studies were decreased sleep efficiency and increased sleep onset latency. Many of these findings could be related to medication used for the treatment of tics and comorbid disorders.

摘要

睡眠障碍似乎是被诊断为妥瑞氏症(TS)或慢性或持续性抽动障碍(CTD或PTD)患者的常见主诉。在本综述中,我们扩展了之前使用的搜索,截至2022年2月15日,使用了4个知名数据库,寻找全球和/或特定睡眠障碍与对TS/CTD/PTD患者进行的多导睡眠图研究的共存情况。该主题的相关参考文献是手动挑选的。一般睡眠障碍、失眠、不同的觉醒障碍、睡眠期间抽动的持续存在、日间过度嗜睡以及睡眠期间周期性肢体运动(PLMS)在TS患者中非常常见,其中大多数在合并注意缺陷多动障碍的患者中更为常见。多导睡眠图研究最常见的结果是睡眠效率降低和入睡潜伏期延长。这些发现中的许多可能与用于治疗抽动和合并症的药物有关。

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