Department of Gastroenterology, the Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530007, China.
Department of Gastroenterology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China.
Arab J Gastroenterol. 2022 Aug;23(3):206-209. doi: 10.1016/j.ajg.2022.06.001. Epub 2022 Jul 30.
The ability to predict severe acute pancreatitis (SAP) at an early stage is crucial for reducing the associated complications and mortality. In this study, we compared the ratio of red cell distribution width to albumin (RDW-to-ALB) using predictive scoring systems, such as the Ranson score, BISAP, and MCTSI, to develop a simple and accurate method of predicting SAP.
We included 212 patients with mild acute pancreatitis (MAP) and 89 with SAP between January 2013 and December 2018. The differences in the general characteristics and biochemical analysis as well as the various predictive scores were compared between the two groups. We evaluated the sensitivity and specificity between the RDW-to-ALB ratio, RDW, ALB, and multiple predictive scores in patients with early acute pancreatitis (AP) by using the receiver operating characteristic (ROC) curve.
The RDW-to-ALB ratio (%) of patients with SAP was higher than that of patients with MAP (0.43 ± 0.08 vs. 0.32 ± 0.04, p < 0.001). Patients with SAP had higher Ranson, BISAP, and MCTSI scores than those with MAP. The ROC curve revealed that, when the RDW-to-ALB ratio (%) was >0.36, the sensitivity and specificity of the predicted SAP were 80.0% and 80.7%, respectively. Further statistical analysis found that the RDW-to-ALB ratio and Ranson, BISAP, and MCTSI scores were consistent in predicting SAP effectiveness (P > 0.05).
The RDW-to-ALB ratio has a promising predictive power for SAP, and its effectiveness is comparable with those of Ranson, BISAP, and MCTSI scores.
早期预测重症急性胰腺炎（SAP）的能力对于降低相关并发症和死亡率至关重要。本研究通过比较红细胞分布宽度与白蛋白比值（RDW-to-ALB）与预测评分系统（如 Ranson 评分、BISAP 和 MCTSI），旨在开发一种简单而准确的 SAP 预测方法。
我们纳入了 2013 年 1 月至 2018 年 12 月间 212 例轻症急性胰腺炎（MAP）和 89 例 SAP 患者。比较两组患者的一般特征、生化分析及各预测评分的差异。通过绘制受试者工作特征（ROC）曲线，评估 RDW-to-ALB 比值、RDW、ALB 与多个预测评分在早期急性胰腺炎（AP）患者中的敏感性和特异性。
SAP 患者的 RDW-to-ALB 比值（%）高于 MAP 患者（0.43±0.08 比 0.32±0.04，p<0.001）。SAP 患者的 Ranson、BISAP 和 MCTSI 评分均高于 MAP 患者。ROC 曲线显示，当 RDW-to-ALB 比值（%）>0.36 时，预测 SAP 的敏感性和特异性分别为 80.0%和 80.7%。进一步的统计学分析发现，RDW-to-ALB 比值与 Ranson、BISAP 和 MCTSI 评分在预测 SAP 效果方面具有一致性（P>0.05）。
RDW-to-ALB 比值对 SAP 具有较好的预测能力，其效果与 Ranson、BISAP 和 MCTSI 评分相当。
