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内镜下真空治疗(EVT)在减重手术后漏和瘘中的应用:系统评价和荟萃分析。

Endoscopic Vacuum Therapy (EVT) for the Treatment of Post-Bariatric Surgery Leaks and Fistulas: a Systematic Review and Meta-analysis.

机构信息

Serviço de Endoscopia Gastrointestinal, Departamento de Gastroenterologia, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Av. Dr Enéas de Carvalho Aguiar, 225, 6o andar, bloco 3, Cerqueira Cesar, São Paulo, SP, 05403-010, Brazil.

Basil I. Hirschowitz Endoscopic Center of Excellence, Division of Gastroenterology & Hepatology, Department of Internal Medicine, The University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL, USA.

出版信息

Obes Surg. 2022 Oct;32(10):3435-3451. doi: 10.1007/s11695-022-06228-0. Epub 2022 Aug 3.

Abstract

Bariatric surgery remains the most effective treatment for morbid obesity and its comorbidities. However, post-surgical leaks and fistulas can occur in about 1-5% of patients, with challenging treatment approaches. Endoscopic vacuum therapy (EVT) has emerged as a promising tool due to its satisfactory results and accessibility. In this first systematic review and meta-analysis on the subject, EVT revealed rates of 87.2% clinical success, 6% moderate adverse events, and 12.5% system dislodgements, requiring 6.47 EVT system exchanges every 4.39 days, with a dwell time of 25.67 days and a total length of hospitalization of 44.43 days. Although our results show that EVT is a safe and effective therapy for post-surgical leaks and fistulas, they should be interpreted with caution due to the paucity of available data.

摘要

减重手术仍然是治疗病态肥胖及其合并症最有效的方法。然而,术后漏和瘘在大约 1-5%的患者中可能发生,治疗方法具有挑战性。内镜下真空治疗(EVT)由于其满意的结果和可及性而成为一种有前途的工具。在这篇关于该主题的首次系统评价和荟萃分析中,EVT 的临床成功率为 87.2%,中度不良事件率为 6%,系统移位率为 12.5%,每 4.39 天需要更换 6.47 个 EVT 系统,留置时间为 25.67 天,总住院时间为 44.43 天。尽管我们的结果表明 EVT 是治疗术后漏和瘘的一种安全有效的治疗方法,但由于可用数据有限,这些结果应谨慎解释。

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