Alberti Joaquin Fernandez, Nardi Walter S, Recalde Maricel, Quildrian Sergio D
Department of General Surgery, Buenos Aires British Hospital, Perdriel 74, Buenos Aires C1280AEB, Argentina.
Retroperitoneal, Pelvic and Adrenal Unit, Department of General Surgery, Buenos Aires British Hospital, Perdriel 74, Buenos Aires C1280AEB, Argentina.
Ecancermedicalscience. 2022 May 23;16:1395. doi: 10.3332/ecancer.2022.1395. eCollection 2022.
Adrenal glands are a common site of metastasis for several types of malignancies. Nevertheless, bilateral metastasis leading to adrenal insufficiency is a very rare presentation.
We present a 62-year-old woman with previous history of colorectal cancer and bilateral adrenal metastasis associated with primary adrenal insufficiency. The patient underwent bilateral open adrenalectomy after a multidisciplinary tumour board evaluation.
The incidence of adrenal insufficiency may be underestimated in patients with a history of cancer. Adrenal function must be evaluated in those patients presenting with bilateral adrenal masses and hormonal replacement therapy should be considered, if appropriate. In selected cases, bilateral adrenalectomy can give a possible therapeutic option for patients with confined disease to the adrenal glands.
肾上腺是多种恶性肿瘤常见的转移部位。然而，双侧转移导致肾上腺功能不全的情况非常罕见。
我们报告一名62岁女性，既往有结直肠癌病史，出现双侧肾上腺转移并伴有原发性肾上腺功能不全。经过多学科肿瘤委员会评估后，该患者接受了双侧开放性肾上腺切除术。
癌症病史患者肾上腺功能不全的发生率可能被低估。对于出现双侧肾上腺肿块的患者，必须评估肾上腺功能，必要时应考虑激素替代治疗。在某些特定病例中，双侧肾上腺切除术可为肾上腺局限性病变患者提供一种可能的治疗选择。
