Bendas Alexandre José Rodrigues, Moreto Pablo Luiz das Neves, Coxo Adriano Baldaia, Holguin Paula Gazé, Soares Denise do Vale
Veterinarian, DSc. Departamento de medicina e cirurgia veterinária (DMCV), Instituto de Veterinária (IV), Universidade Federal Rural do Rio de Janeiro (UFRRJ). Campus Seropédica, RJ, Brazil.
Veterinarian, Autonomus, Rio de Janeiro, RJ, Brazil.
Braz J Vet Med. 2022 Jul 26;44:e001422. doi: 10.29374/2527-2179.bjvm001422. eCollection 2022.
Transmissible venereal tumor (TVT) is a malignant round cell neoplasm that primarily affects the genital region of dogs. Despite being sexually transmitted, transmission can occur through contact with mucous membranes and cutaneous tissue. Although less routine, TVT has been described in several extragenital regions, such as the nasal plane, oral cavity, eyeball, eyelid, and anus. Although metastases are infrequent, they can occur in the skin, inguinal lymph nodes, liver, kidneys, spleen, intestine, heart, brain, lungs, and other organs. The clinical signs of TVT are usually related to serosanguineous secretion, intense odor, deformity, ulceration, and possibly areas of necrosis. In cases of metastases, clinical signs will depend on the affected organ. The treatment of choice for TVT is chemotherapy with vincristine. The present study aimed to report the case of a 2-year-old mixed-breed canine with intra-abdominal nodules detected by ultrasound examination, which were later diagnosed as a TVT by histopathology and immunohistochemistry.
传染性性病肿瘤（TVT）是一种恶性圆形细胞瘤，主要影响犬类的生殖区域。尽管它是通过性传播的，但也可通过与粘膜和皮肤组织接触而传播。虽然不太常见，但TVT已在几个生殖器外区域被描述，如鼻面部、口腔、眼球、眼睑和肛门。虽然转移很少见，但可发生于皮肤、腹股沟淋巴结、肝脏、肾脏、脾脏、肠道、心脏、大脑、肺和其他器官。TVT的临床症状通常与血清血性分泌物、强烈气味、畸形、溃疡以及可能的坏死区域有关。在发生转移的情况下，临床症状将取决于受影响的器官。TVT的首选治疗方法是用长春新碱进行化疗。本研究旨在报告一例2岁的混血犬病例，该犬经超声检查发现腹腔内有结节，随后经组织病理学和免疫组织化学诊断为TVT。
