Swei Eric C, Brar Anantnoor K, Rice Jonathan D, Kim Ike I, Knez Virginia M, Doe Christopher F, Forman Lisa M
Division of Gastroenterology, University of Colorado School of Medicine, Aurora, CO.
Division of Internal Medicine, University of Colorado School of Medicine, Aurora, CO.
ACG Case Rep J. 2022 May 4;9(5):e00774. doi: 10.14309/crj.0000000000000774. eCollection 2022 May.
Rhabdomyolysis is a known rare and potentially lethal complication of statin use. This toxic effect is potentiated by alterations in hepatic physiology in patients with cirrhosis. Transjugular intrahepatic portosystemic shunt placement has the potential to further compound this effect; yet, examples of this have not previously been described in the literature. We present a case of a patient who experienced statin-induced rhabdomyolysis likely as a direct consequence of transjugular intrahepatic portosystemic shunt placement.
横纹肌溶解是已知的使用他汀类药物罕见且可能致命的并发症。肝硬化患者肝脏生理功能的改变会增强这种毒性作用。经颈静脉肝内门体分流术有可能进一步加剧这种影响；然而，此前文献中尚未描述过此类病例。我们报告一例患者，其经历的他汀类药物诱导的横纹肌溶解可能是经颈静脉肝内门体分流术直接导致的后果。
