Corbella Stefano, Walter Clemens, Tsesis Igor
Department of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, Milan, Italy.
IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Int Endod J. 2023 Oct;56 Suppl 3:487-498. doi: 10.1111/iej.13808. Epub 2022 Aug 12.
To manage apical periodontitis in root filled maxillary and mandibular molars, root resection techniques may be employed to avoid the loss of the tooth.
The objectives of the study were to systematically analyse the effectiveness of root resection techniques (root resection/crown resection/root amputation) for the management of apical periodontitis with non-surgical root canal retreatment or apical surgery by the evaluation of clinical and patient-related outcomes (PROMS), in human experimental studies and longitudinal studies.
An electronic literature search in PubMed, MEDLINE via OVID interface, EMBASE and Cochrane Central, supplemented by a manual hand search of the grey literature, was performed up to 25th September 2021. Randomized controlled trials, comparative clinical trials and observational studies reporting on the outcome (tooth survival and patient-reported outcome measures with a minimum follow-up of 1 year) of root resection techniques for treating apical periodontitis were identified. The risk of bias was evaluated using the Newcastle-Ottawa scale.
From a total of 2098 reports, 36 were considered for further screening. Three retrospective studies, published between 2018 and 2020, were included in this systematic review. A high heterogeneity in terms of protocols, study design and the reported outcomes were observed. The risk of bias was scored as low to moderate. These three studies consisted of data from 305 resected teeth, from 254 patients, with a follow-up period of 1-16.8 years. Overall, 151 teeth were extracted during the follow-up period. In these studies, root resection treatment was carried out on 42 teeth exclusively for endodontic reasons. One of these studies reported 12 out of 23 teeth lost at follow-up. None of the studies reported on PROMS.
Although root resection techniques may be used for treating teeth with apical periodontitis, the data are limited. Furthermore, the studies are very heterogeneous and associated with high risk of bias.
Given the current level of available evidence, it is not possible to recommend, or dismiss, root resection techniques for managing apical periodontitis.
PROSPERO database (CRD42021260306).
为了处理根管充填后的上颌和下颌磨牙根尖周炎,可采用牙根切除术以避免牙齿缺失。
本研究的目的是通过评估临床和患者相关结局(患者报告结局量表),在人体实验研究和纵向研究中,系统分析牙根切除术(牙根切除/冠切除/根切断术)联合非手术根管再治疗或根尖手术治疗根尖周炎的有效性。
截至2021年9月25日,在PubMed、通过OVID界面的MEDLINE、EMBASE和Cochrane中心进行电子文献检索,并辅以对灰色文献的手工检索。纳入报告牙根切除术治疗根尖周炎结局(牙齿存留率和患者报告结局量表,最短随访1年)的随机对照试验、比较临床试验和观察性研究。使用纽卡斯尔-渥太华量表评估偏倚风险。
从总共2098篇报告中,筛选出36篇进行进一步筛选。本系统评价纳入了2018年至2020年发表的三项回顾性研究。在方案、研究设计和报告结局方面观察到高度异质性。偏倚风险评分为低到中度。这三项研究包含来自254例患者的305颗切除牙齿的数据,随访期为1至16.8年。总体而言,随访期间拔除了151颗牙齿。在这些研究中,仅因牙髓原因对42颗牙齿进行了牙根切除治疗。其中一项研究报告随访时23颗牙齿中有12颗缺失。没有研究报告患者报告结局量表情况。
尽管牙根切除术可用于治疗根尖周炎的牙齿,但数据有限。此外,这些研究非常异质且偏倚风险高。
鉴于现有证据水平,无法推荐或摒弃牙根切除术治疗根尖周炎。
PROSPERO数据库(CRD42021260306)