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SARS CoV-2 抗体阳性猫的临床、病毒学、影像学和病理学发现。

Clinical, virological, imaging and pathological findings in a SARS CoV-2 antibody positive cat.

机构信息

Zeytinburnu Veterinary Clinic, Merv Caddesi, 34025 Zeytinburnu, Istanbul, Turkey.

Department of Virology, Veterinary Faculty, Istanbul University-Cerrahpasa, 34500 Buyukcekmece, Istanbul, Turkey.

出版信息

J Vet Sci. 2022 Jul;23(4):e52. doi: 10.4142/jvs.21310.

DOI:10.4142/jvs.21310
PMID:35920120
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9346522/
Abstract

This paper reports a presumptive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in a cat. A cat with respiratory disease living with three individuals with coronavirus disease 2019 showed bilateral ground-glass opacities in the lung on X-ray and computed tomography. The clinical swabs were negative for SARS-CoV-2 RNA, but the serum was positive for SARS-CoV-2 antibodies. Interstitial pneumonia and prominent type 2 pneumocyte hyperplasia were noted on histopathology. Respiratory tissues were negative for SARS-CoV-2 RNA or antigen, but the cat was positive for feline parvovirus DNA. In conclusion, the respiratory disease and associated pathology in this cat could have been due to exposure to SARS-CoV-2.

摘要

本文报告了一例疑似严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）感染的猫病例。一只与三名 2019 年冠状病毒病患者生活在一起的患呼吸道疾病的猫在 X 射线和计算机断层扫描中显示肺部双侧磨玻璃样混浊。临床拭子 SARS-CoV-2 RNA 检测为阴性，但血清 SARS-CoV-2 抗体为阳性。组织病理学检查显示间质性肺炎和明显的 2 型肺泡细胞增生。呼吸道组织中未检测到 SARS-CoV-2 RNA 或抗原，但猫的细小病毒 DNA 为阳性。总之，这只猫的呼吸道疾病和相关病理可能是由于接触 SARS-CoV-2 引起的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b199/9346522/39fb9b78cb3c/jvs-23-e52-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b199/9346522/15b9c50bf61a/jvs-23-e52-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b199/9346522/04a500306037/jvs-23-e52-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b199/9346522/39fb9b78cb3c/jvs-23-e52-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b199/9346522/15b9c50bf61a/jvs-23-e52-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b199/9346522/04a500306037/jvs-23-e52-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b199/9346522/39fb9b78cb3c/jvs-23-e52-g003.jpg

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