• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

通过对一只意大利宠物猫的咽拭子进行逆转录定量聚合酶链反应(RT-qPCR)检测到新型严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染。

New SARS-CoV-2 Infection Detected in an Italian Pet Cat by RT-qPCR from Deep Pharyngeal Swab.

作者信息

Musso Nicolò, Costantino Angelita, La Spina Sebastiano, Finocchiaro Alessandra, Andronico Francesca, Stracquadanio Stefano, Liotta Luigi, Visalli Rosanna, Emmanuele Giovanni

机构信息

Section of Microbiology, Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.

Department of Drug Sciences, University of Catania, 95125 Catania, Italy.

出版信息

Pathogens. 2020 Sep 11;9(9):746. doi: 10.3390/pathogens9090746.

DOI:10.3390/pathogens9090746
PMID:32932800
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7559392/
Abstract

The pandemic respiratory disease COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in Wuhan in December 2019 and then spread throughout the world; Italy was the most affected European country. Despite close pet-human contact, little is known about the predisposition of pets to SARS-CoV-2. Among these, felines are the most susceptible. In this study, a domestic cat with clear clinical signs of pneumonia, confirmed by Rx imaging, was found to be infected by SARS-CoV-2 using quantitative RT-qPCR from a nasal swab. This is the first Italian study responding to the request of the scientific community to focus attention on the possible role of pets as a viral reservoir. An important question remains unanswered: did the cat actually die due to SARS-CoV-2 infection?

摘要

由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的大流行性呼吸道疾病COVID-19于2019年12月在武汉出现,随后蔓延至全球;意大利是受影响最严重的欧洲国家。尽管宠物与人类密切接触,但关于宠物对SARS-CoV-2的易感性知之甚少。其中,猫科动物最为易感。在本研究中,一只经X线成像确诊有明确肺炎临床症状的家猫,通过对鼻拭子进行定量RT-qPCR检测,发现感染了SARS-CoV-2。这是意大利第一项响应科学界要求、关注宠物作为病毒宿主可能作用的研究。一个重要问题仍未得到解答:这只猫是否真的死于SARS-CoV-2感染?

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/586c/7559392/d317dc56a580/pathogens-09-00746-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/586c/7559392/d317dc56a580/pathogens-09-00746-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/586c/7559392/d317dc56a580/pathogens-09-00746-g001.jpg

相似文献

1
New SARS-CoV-2 Infection Detected in an Italian Pet Cat by RT-qPCR from Deep Pharyngeal Swab.通过对一只意大利宠物猫的咽拭子进行逆转录定量聚合酶链反应(RT-qPCR)检测到新型严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染。
Pathogens. 2020 Sep 11;9(9):746. doi: 10.3390/pathogens9090746.
2
Preliminary study of coronavirus disease 2019 on pets in pandemic in Denpasar, Bali, Indonesia.印度尼西亚巴厘岛登巴萨新冠疫情期间宠物感染2019冠状病毒病的初步研究
Vet World. 2021 Nov;14(11):2979-2983. doi: 10.14202/vetworld.2021.2979-2983. Epub 2021 Nov 26.
3
SARS-CoV-2 in Domestic UK Cats from Alpha to Omicron: Swab Surveillance and Case Reports.英国国内家猫中从阿尔法到奥密克戎变异株的 SARS-CoV-2:拭子监测和病例报告。
Viruses. 2023 Aug 19;15(8):1769. doi: 10.3390/v15081769.
4
Detection of SARS-CoV-2 variant B.1.1.7 in a cat in Germany.德国一只猫中检测到 SARS-CoV-2 变异株 B.1.1.7。
Res Vet Sci. 2021 Nov;140:229-232. doi: 10.1016/j.rvsc.2021.09.008. Epub 2021 Sep 9.
5
Sensitive tracking of circulating viral RNA through all stages of SARS-CoV-2 infection.通过 SARS-CoV-2 感染的所有阶段对循环病毒 RNA 进行敏感跟踪。
J Clin Invest. 2021 Apr 1;131(7). doi: 10.1172/JCI146031.
6
First reported cases of SARS-CoV-2 infection in pets in São Paulo, Brazil.巴西圣保罗首次报告宠物感染新型冠状病毒病例。
Vet World. 2022 Nov;15(11):2593-2596. doi: 10.14202/vetworld.2022.2593-2596. Epub 2022 Nov 16.
7
First detection and genome sequencing of SARS-CoV-2 in an infected cat in France.法国一只感染新冠病毒的猫中首次检测到并测序到 SARS-CoV-2 病毒。
Transbound Emerg Dis. 2020 Nov;67(6):2324-2328. doi: 10.1111/tbed.13659. Epub 2020 Jun 23.
8
SARS-CoV-2 in fruit bats, ferrets, pigs, and chickens: an experimental transmission study.果蝠、雪貂、猪和鸡中 SARS-CoV-2:一项实验性传播研究。
Lancet Microbe. 2020 Sep;1(5):e218-e225. doi: 10.1016/S2666-5247(20)30089-6. Epub 2020 Jul 7.
9
First detection and molecular analysis of SARS-CoV-2 from a naturally infected cat from Argentina.首次从阿根廷一只自然感染的猫中检测到并分析了 SARS-CoV-2。
Vet Microbiol. 2021 Sep;260:109179. doi: 10.1016/j.vetmic.2021.109179. Epub 2021 Jul 8.
10
Severe acute respiratory syndrome-coronavirus 2 in domesticated animals and its potential of transmission: A meta-analysis.家畜中的严重急性呼吸综合征冠状病毒2及其传播潜力:一项荟萃分析。
Vet World. 2021 Oct;14(10):2782-2792. doi: 10.14202/vetworld.2021.2782-2792. Epub 2021 Oct 27.

引用本文的文献

1
Evaluation of RT-LAMP for SARS-CoV-2 Detection in Animal Feces.用于检测动物粪便中新型冠状病毒的逆转录环介导等温扩增技术评估
Viruses. 2025 May 29;17(6):783. doi: 10.3390/v17060783.
2
Higher Frequency of SARS-CoV-2 RNA Shedding by Cats than Dogs in Households with Owners Recently Diagnosed with COVID-19.与近期被诊断患有 COVID-19 的主人同住的家庭中,猫比狗的 SARS-CoV-2 RNA 脱落频率更高。
Viruses. 2024 Oct 11;16(10):1599. doi: 10.3390/v16101599.
3
Electrophysiological properties and structural prediction of the SARS-CoV-2 viroprotein E.严重急性呼吸综合征冠状病毒2病毒蛋白E的电生理特性及结构预测

本文引用的文献

1
From People to : Natural SARS-CoV-2 Infection in Tigers and Lions at the Bronx Zoo.从人到:布朗克斯动物园的老虎和狮子中自然发生的 SARS-CoV-2 感染。
mBio. 2020 Oct 13;11(5):e02220-20. doi: 10.1128/mBio.02220-20.
2
Sensitivity assessment of droplet digital PCR for SARS-CoV-2 detection.用于 SARS-CoV-2 检测的液滴数字 PCR 灵敏度评估。
Int J Mol Med. 2020 Sep;46(3):957-964. doi: 10.3892/ijmm.2020.4673. Epub 2020 Jul 13.
3
Evidence for SARS-CoV-2 Infection of Animal Hosts.严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染动物宿主的证据。
Front Mol Biosci. 2024 Mar 28;11:1334819. doi: 10.3389/fmolb.2024.1334819. eCollection 2024.
4
Development and validation of multiplex one-step qPCR/RT-qPCR assays for simultaneous detection of SARS-CoV-2 and pathogens associated with feline respiratory disease complex.开发和验证用于同时检测 SARS-CoV-2 和与猫呼吸道疾病综合征相关病原体的多重一步 qPCR/RT-qPCR 检测方法。
PLoS One. 2024 Mar 22;19(3):e0297796. doi: 10.1371/journal.pone.0297796. eCollection 2024.
5
Assessing the Potential Role of Cats () as Generators of Relevant SARS-CoV-2 Lineages during the Pandemic.评估猫在疫情期间作为相关严重急性呼吸综合征冠状病毒2(SARS-CoV-2)谱系产生者的潜在作用。
Pathogens. 2023 Nov 16;12(11):1361. doi: 10.3390/pathogens12111361.
6
SARS-CoV-2 and Companion Animals: Sources of Information and Communication Campaign during the COVID-19 Pandemic in Italy.严重急性呼吸综合征冠状病毒2与伴侣动物:意大利新冠疫情期间的信息来源及宣传活动
Vet Sci. 2023 Jun 30;10(7):426. doi: 10.3390/vetsci10070426.
7
Interspecies transmission of SARS CoV-2 with special emphasis on viral mutations and ACE-2 receptor homology roles.严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的跨物种传播,特别强调病毒突变和血管紧张素转换酶2(ACE-2)受体同源性的作用。
Int J Vet Sci Med. 2023 Jul 10;11(1):55-86. doi: 10.1080/23144599.2023.2222981. eCollection 2023.
8
SARS-CoV-2 infection of companion animals in Egypt and its risk of spillover.埃及宠物动物感染 SARS-CoV-2 及其溢出风险。
Vet Med Sci. 2023 Jan;9(1):13-24. doi: 10.1002/vms3.1029. Epub 2022 Dec 14.
9
Clinical, virological, imaging and pathological findings in a SARS CoV-2 antibody positive cat.SARS CoV-2 抗体阳性猫的临床、病毒学、影像学和病理学发现。
J Vet Sci. 2022 Jul;23(4):e52. doi: 10.4142/jvs.21310.
10
Severe acute respiratory syndrome coronavirus 2 in cats: a systematic review.猫体内的严重急性呼吸综合征冠状病毒2:一项系统综述。
Braz J Vet Med. 2021 Jun 1;43:e000421. doi: 10.29374/2527-2179.bjvm000421. eCollection 2021.
Pathogens. 2020 Jun 30;9(7):529. doi: 10.3390/pathogens9070529.
4
COVID-19 infection: the China and Italy perspectives.新型冠状病毒肺炎感染:中国与意大利的观点。
Cell Death Dis. 2020 Jun 8;11(6):438. doi: 10.1038/s41419-020-2603-0.
5
First detection and genome sequencing of SARS-CoV-2 in an infected cat in France.法国一只感染新冠病毒的猫中首次检测到并测序到 SARS-CoV-2 病毒。
Transbound Emerg Dis. 2020 Nov;67(6):2324-2328. doi: 10.1111/tbed.13659. Epub 2020 Jun 23.
6
COVID-19 in felines, their role in human health and possible implications for their guardians and health surveillance.猫科动物中的新冠病毒、它们在人类健康中的作用以及对其监护人及健康监测的潜在影响。
Epidemiol Serv Saude. 2020;29(2):e2020228. doi: 10.5123/s1679-49742020000300005. Epub 2020 May 15.
7
Modelling the COVID-19 epidemic and implementation of population-wide interventions in Italy.对意大利 COVID-19 疫情的建模与全民干预措施的实施。
Nat Med. 2020 Jun;26(6):855-860. doi: 10.1038/s41591-020-0883-7. Epub 2020 Apr 22.
8
Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2.雪貂、猫、狗和其他驯养动物对 SARS-CoV-2 的易感性。
Science. 2020 May 29;368(6494):1016-1020. doi: 10.1126/science.abb7015. Epub 2020 Apr 8.
9
Coronavirus can infect cats - dogs, not so much.冠状病毒会感染猫——狗则不那么容易感染。
Nature. 2020 Apr 1. doi: 10.1038/d41586-020-00984-8.
10
Spike protein recognition of mammalian ACE2 predicts the host range and an optimized ACE2 for SARS-CoV-2 infection.刺突蛋白对哺乳动物 ACE2 的识别预测了宿主范围和用于 SARS-CoV-2 感染的优化 ACE2。
Biochem Biophys Res Commun. 2020 May 21;526(1):165-169. doi: 10.1016/j.bbrc.2020.03.047. Epub 2020 Mar 19.