Division of Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Placenta. 2022 Sep;127:8-11. doi: 10.1016/j.placenta.2022.07.016. Epub 2022 Jul 22.
To study the relative importance of clinical and umbilical cord (UC) risk factors for placental fetal vascular malperfusion (FVM), 52 placentas with clinical UC compromise were compared with 204 placentas with other maternal/fetal conditions predisposing to FVM, 286 placentas with both factors, and 38 placentas with no clinical conditions or UC factors predisposing to FVM. FVM, both distal villous and global, was more common with UC compromise. Cases with isolated UC compromise were associated with more unfavorable clinical outcomes and histological distal FVM. Clinical conditions without umbilical cord compromise were not associated with increased rate of FVM.
为了研究临床和脐带（UC）危险因素对胎盘胎儿血管灌注不良（FVM）的相对重要性，将 52 例临床 UC 受损的胎盘与 204 例易发生 FVM 的其他母体/胎儿情况的胎盘、286 例同时存在这两个因素的胎盘和 38 例无临床情况或 UC 因素易发生 FVM 的胎盘进行了比较。UC 受损时，远端绒毛和整体 FVM 更为常见。单纯 UC 受损的病例与更不利的临床结局和组织学远端 FVM 相关。无 UC 受损的临床情况与 FVM 发生率增加无关。
