University of South Florida Morsani College of Medicine, Tampa, FL.
Lehigh Valley Health Network Department of Surgery.
Neurologist. 2023 May 1;28(3):187-189. doi: 10.1097/NRL.0000000000000456.
Carotid webs are shelf-like projections of the carotid bulb lumen associated with ipsilateral ischemic stroke in young patients. Given its rarity, a limited number of studies have evaluated the optimal management of symptomatic carotid webs to prevent further ischemic stroke.
A 40-year-old Caucasian man presented with a sudden onset of left-sided facial droop, hemiparesis, and dysarthria. Computed tomography angiography revealed occlusion of the distal M1 and proximal M2 segments of the right middle cerebral artery and a small intimal flap at the right internal carotid artery origin. Intravenous alteplase was administered without clinical improvement. The patient underwent successful mechanical thrombectomy with complete revascularization of the middle cerebral artery and no residual neurologic deficits. Magnetic resonance angiography confirmed a curvilinear, shelf-like projection from the right carotid bulb posterior wall, consistent with a carotid web. The patient underwent carotid endarterectomy with no complications and was discharged home with no residual deficits or recurrence of stroke.
No randomized, controlled prospective studies have compared the efficacy of endarterectomy to carotid artery stenting in patients with symptomatic carotid web. This case emphasizes the importance of considering carotid web as an embolic source of stroke in the young and provides support for revascularization as a safe and effective mean of secondary stroke prevention.
颈动脉壁是颈动脉窦腔的板状突起,与年轻患者同侧缺血性卒中有关。鉴于其罕见性,只有少数研究评估了有症状颈动脉壁的最佳治疗方法,以预防进一步的缺血性卒中。
一名 40 岁的白种人男性突发左侧面瘫、偏瘫和构音障碍。计算机断层血管造影显示右侧大脑中动脉 M1 段远端和 M2 段近端闭塞,以及右侧颈内动脉起始处有一小片内膜瓣。静脉注射阿替普酶后无临床改善。患者成功接受了机械血栓切除术,大脑中动脉完全再通,无残留神经功能缺损。磁共振血管造影证实右侧颈动脉窦后壁有一条曲线状、板状突起,符合颈动脉壁。患者行颈动脉内膜切除术,无并发症,出院时无残留缺损或卒中复发。
没有随机、对照前瞻性研究比较过有症状颈动脉壁患者行颈动脉内膜切除术与颈动脉支架置入术的疗效。本病例强调了将颈动脉壁视为年轻患者卒中栓子来源的重要性,并为血管再通作为二级卒中预防的安全有效方法提供了支持。