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随机试验儿童和青少年抑郁预防摘要报告质量：对摘要遵循 CONSORT 的meta 流行病学研究。

Reporting quality for abstracts of randomised trials on child and adolescent depression prevention: a meta-epidemiological study on adherence to CONSORT for abstracts.

机构信息

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Public Health, Berlin, Germany

Department of Population Medicine and Health Services Research, Bielefeld School of Public Health, Universität Bielefeld, Bielefeld, Germany.

出版信息

BMJ Open. 2022 Aug 3;12(8):e061873. doi: 10.1136/bmjopen-2022-061873.

DOI:10.1136/bmjopen-2022-061873
PMID:35922097
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9352996/
Abstract

OBJECTIVES: This study aimed to investigate adherence to Consolidated Standards of Reporting Trials (CONSORT) for abstracts in reports of randomised trials on child and adolescent depression prevention. Secondary objective was to examine factors associated with overall reporting quality. DESIGN: Meta-epidemiological study. DATA SOURCES: We searched MEDLINE, EMBASE, PsycINFO, PsycArticles and CENTRAL. ELIGIBILITY CRITERIA: Trials were eligible if the sample consisted of children and adolescents under 18 years with or without an increased risk for depression or subthreshold depression. We included reports published from 1 January 2003 to 8 August 2020 on randomised controlled trials (RCTs) and cluster randomised trials (CRTs) assessing universal, selective and indicated interventions aiming to prevent the onset of depression or reducing depressive symptoms. DATA EXTRACTION AND SYNTHESIS: As the primary outcome measure, we assessed for each trial abstract whether information recommended by CONSORT was adequately reported, inadequately reported or not reported. Moreover, we calculated a summative score of overall reporting quality and analysed associations with trial and journal characteristics. RESULTS: We identified 169 eligible studies, 103 (61%) RCTs and 66 (39%) CRTs. Adequate reporting varied considerably across CONSORT items: while 9 out of 10 abstracts adequately reported the study objective, no abstract adequately provided information on blinding. Important adverse events or side effects were only adequately reported in one out of 169 abstracts. Summative scores for the abstracts' overall reporting quality ranged from 17% to 83%, with a median of 40%. Scores were associated with the number of authors, abstract word count, journal impact factor, year of publication and abstract structure. CONCLUSIONS: Reporting quality for abstracts of trials on child and adolescent depression prevention is suboptimal. To help health professionals make informed judgements, efforts for improving adherence to reporting guidelines for abstracts are needed.

摘要

目的：本研究旨在调查报告儿童和青少年抑郁预防随机试验的摘要中对 CONSORT 标准的遵守情况。次要目的是检验与整体报告质量相关的因素。

设计：meta-流行病学研究。

资料来源：我们检索了 MEDLINE、EMBASE、PsycINFO、PsycArticles 和 CENTRAL。

入选标准：如果样本包括 18 岁以下的儿童和青少年，无论是否有抑郁或阈下抑郁的风险增加，且试验为随机对照试验（RCT）和整群随机试验（CRT），评估普遍性、选择性和针对性干预措施，旨在预防抑郁发作或减少抑郁症状，则试验符合纳入标准。

数据提取和综合：作为主要结局指标，我们评估了每个试验摘要中 CONSORT 推荐的信息是否充分报告、不充分报告或未报告。此外，我们计算了整体报告质量的综合评分，并分析了与试验和期刊特征的关联。

结果：我们确定了 169 项符合条件的研究，其中 103 项（61%）为 RCT 和 66 项（39%）为 CRT。在 CONSORT 项目中，充分报告的情况差异很大：虽然 10 个摘要中有 9 个充分报告了研究目的，但没有摘要充分报告了盲法。只有 169 个摘要中的 1 个充分报告了重要的不良事件或副作用。摘要整体报告质量的综合评分范围为 17%至 83%，中位数为 40%。评分与作者人数、摘要字数、期刊影响因子、出版年份和摘要结构有关。

结论：儿童和青少年抑郁预防试验摘要的报告质量不理想。为了帮助卫生专业人员做出明智的判断，需要努力提高对摘要报告指南的遵守。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef15/9352996/70943cf001d8/bmjopen-2022-061873f04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef15/9352996/524f4b28a269/bmjopen-2022-061873f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef15/9352996/e375a8dc7d5b/bmjopen-2022-061873f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef15/9352996/8438616d8066/bmjopen-2022-061873f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef15/9352996/70943cf001d8/bmjopen-2022-061873f04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef15/9352996/524f4b28a269/bmjopen-2022-061873f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef15/9352996/e375a8dc7d5b/bmjopen-2022-061873f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef15/9352996/8438616d8066/bmjopen-2022-061873f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef15/9352996/70943cf001d8/bmjopen-2022-061873f04.jpg

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本文引用的文献

[1]
Reporting quality of abstracts of randomized controlled trials related to implant dentistry.

J Periodontol. 2021-9-13

[2]
Assessment of reporting quality in randomised controlled clinical trial abstracts of dental implantology published from 2014 to 2016.

BMJ Open. 2021-8-13

[3]
Abstracts for reports of randomised trials of COVID-19 interventions had low quality and high spin.

J Clin Epidemiol. 2021-7-2

[4]
Abstracts of published randomised controlled trials in Endodontics: Reporting quality and spin.

Int Endod J. 2020-4-25

[5]
Reporting quality and spin in abstracts of randomized clinical trials of periodontal therapy and cardiovascular disease outcomes.

PLoS One. 2020-4-17

[6]
CONSORT endorsement improves the quality of reports of randomized clinical trials in dentistry.

J Clin Epidemiol. 2020-6

[7]
The Reporting Quality of Randomized Controlled Trial Abstracts in Plastic Surgery.

Aesthet Surg J. 2020-2-17

[8]
Reporting quality of randomised controlled trial abstracts presented at the SLEEP Annual Meetings: a cross-sectional study.

BMJ Open. 2019-7-16

[9]
Reporting Quality of Journal Abstracts for Surgical Randomized Controlled Trials Before and After the Implementation of the CONSORT Extension for Abstracts.

World J Surg. 2019-10-15

[10]
Scoping review on interventions to improve adherence to reporting guidelines in health research.

BMJ Open. 2019-5-9

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