在睡眠年会上发表的随机对照试验摘要的报告质量：一项横断面研究。
Reporting quality of randomised controlled trial abstracts presented at the SLEEP Annual Meetings: a cross-sectional study.
作者信息
Hua Fang, Sun Qiao, Zhao Tingting, Chen Xiong, He Hong
机构信息
Centre for Evidence-Based Stomatology, Hubei-MOST KLOS & KLOBM, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
Cochrane Oral Health, Division of Dentistry, The University of Manchester, Manchester, UK.
出版信息
BMJ Open. 2019 Jul 16;9(7):e029270. doi: 10.1136/bmjopen-2019-029270.
OBJECTIVES
To evaluate the reporting quality of randomised controlled trial (RCT) abstracts presented at a leading international conference in sleep medicine (the SLEEP Annual Meeting), and to investigate the association between potential predictors and the reporting quality of trial abstracts in this field.
DESIGN
Cross-sectional, research on research study.
METHODS
A handsearch of the 2016-2018 SLEEP Annual Meeting abstract books was carried out to identify abstracts describing RCTs. Quality of reporting was assessed with the original 17-item CONSORT for Abstracts checklist. Univariable and multivariable linear regression analyses were performed to identify significant predictors of reporting quality. In addition, risk ratios were used to analyse the adequate reporting rate of each quality item by type of intervention and funding status.
PRIMARY AND SECONDARY OUTCOME MEASURES
The overall quality score (OQS, range 0-17) in accordance with the CONSORT for Abstracts checklist (primary outcome), and the adequate reporting rate of each checklist item (secondary outcome).
RESULTS
A total of 176 RCT abstracts were included and assessed. The mean OQS was 5.53 (95% CI 5.30 to 5.76). Only three quality items (, and ) were adequately reported in most abstracts (>75%). None of the abstracts adequately reported , or . According to the multivariable analysis, pharmacological interventions (p=0.018) and funding from the industry (p=0.025) were significantly associated with better reporting quality.
CONCLUSIONS
The reporting quality of RCT abstracts presented at SLEEP Annual Meetings was suboptimal. Pharmacological intervention and funding from industry were significant predictors of better reporting quality. Joint efforts by authors and conference committees are needed to enhance the reporting quality of RCT abstracts presented at sleep medicine conferences, and thereby reduce relevant research waste in this field.
目的
评估在睡眠医学领域的一个重要国际会议（睡眠年会）上发表的随机对照试验（RCT）摘要的报告质量，并调查潜在预测因素与该领域试验摘要报告质量之间的关联。
设计
横断面的研究性研究。
方法
对2016 - 2018年睡眠年会摘要集进行人工检索，以识别描述RCT的摘要。使用原始的17项摘要CONSORT清单评估报告质量。进行单变量和多变量线性回归分析，以确定报告质量的显著预测因素。此外，使用风险比按干预类型和资金状况分析每个质量项目的充分报告率。
主要和次要结局指标
根据摘要CONSORT清单得出的总体质量评分（OQS，范围0 - 17）（主要结局），以及每个清单项目的充分报告率（次要结局）。
结果
共纳入并评估了176篇RCT摘要。平均OQS为5.53（95%CI 5.30至5.76）。大多数摘要（>75%）中只有三个质量项目（、和）得到了充分报告。没有一篇摘要充分报告了、或。根据多变量分析，药物干预（p = 0.018）和行业资金（p = 0.025）与更好的报告质量显著相关。
结论
在睡眠年会上发表的RCT摘要的报告质量欠佳。药物干预和行业资金是报告质量更好的显著预测因素。作者和会议委员会需要共同努力，提高睡眠医学会议上发表的RCT摘要的报告质量，从而减少该领域的相关研究浪费。
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