Hutter Tanya, Collings Thomas S, Kostova Gratsiela, Karet Frankl Fiona E
Materials Science and Engineering Program & Texas Materials Institute, The University of Texas at Austin USA
Kalium Health Ltd UK.
Sens Diagn. 2022 Jun 6;1(4):614-626. doi: 10.1039/d2sd00062h. eCollection 2022 Jul 14.
Potassium is an important bodily electrolyte which is kept within tight limits in health. Many medical conditions as well as commonly-used drugs either raise or lower blood potassium levels, which can be dangerous or even fatal. For at-risk patients, frequent monitoring of potassium can improve safety and lifestyle, but conventional venous blood draws are inconvenient, don't provide a timely result and may be inaccurate. This review summarises current solutions and recent developments in point-of-care and self-testing potassium measurement technologies, which include devices for measurement of potassium in venous blood, devices for home blood collection and remote measurement, devices for rapid home measurement of potassium, wearable sensors for potassium in interstitial fluid, in sweat, in urine, as well as non-invasive potassium detection. We discuss the practical and clinical applicability of these technologies and provide future outlooks.
钾是一种重要的人体电解质,在健康状态下其水平保持在严格的范围内。许多医疗状况以及常用药物都会使血钾水平升高或降低,这可能是危险的甚至是致命的。对于高危患者,频繁监测血钾可以提高安全性并改善生活方式,但传统的静脉采血不方便,不能及时提供结果,而且可能不准确。本综述总结了即时检测和自我检测血钾测量技术的当前解决方案和最新进展,其中包括用于测量静脉血钾的设备、用于家庭采血和远程测量的设备、用于在家中快速测量血钾的设备、用于检测间质液、汗液、尿液中钾的可穿戴传感器,以及无创钾检测。我们讨论了这些技术的实际和临床适用性,并给出了未来展望。