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[低收入环境下采用微脉冲技术经巩膜睫状体光凝术治疗青光眼]

[Glaucoma treatment by transscleral cyclophotocoagulation in micropulse technology in a low-income setting].

作者信息

Kotula Martin Andreas, Paust Karsten, Wirdemann Arno, Msigomba Erick, Burusu Liberator

机构信息

Augenzentrum am St. Franziskus-Hospital, Hohenzollernring 74, 48145, Münster, Deutschland.

Augenärztliche Gemeinschaftspraxis Bonner Augen, Bonn, Deutschland.

出版信息

Ophthalmologie. 2022 Dec;119(12):1275-1279. doi: 10.1007/s00347-022-01668-6. Epub 2022 Jun 9.

Abstract

BACKGROUND

Glaucoma is the leading cause of irreversible blindness worldwide. The prevalence of glaucoma is particularly high in rural regions of Tanzania. Poverty and an inadequate ophthalmic infrastructure increase the difficulty of glaucoma treatment.

OBJECTIVE

Due to the limited access to eye drops or surgical therapy, the effectiveness of transscleral cyclophotocoagulation in micropulse technology (CPC-M) in advanced glaucoma was investigated in the present study.

MATERIALS AND METHODS

We included n = 50 eyes of 35 adult patients with advanced glaucoma and a glaucoma-typical papillary excavation with cupdisc ratio (CDR) ≥ 0.9, regardless of the glaucoma entity. The mean intraocular pressure (IOP) prior to treatment was 34 mm Hg (± 14 mm Hg). The operation was performed under retrobulbar anesthesia with the A.R.C. FOX 810 diode laser (A.R.C. Laser, Nuremberg, Germany; mean energy 127 J ± 10 J).

RESULTS

An IOP between 6 and 21 mm Hg or an IOP reduction by at least 20% of the initial value was defined as success. The success criteria were met by 71% of reevaluated eyes (n = 21) 3 months after treatment, and mean IOP was 19 mm Hg (± 13 mm Hg). Mean IOP 9 months postoperatively (n = 20) was 18 mm Hg (± 10 mm Hg) and the success criteria were met in 65% of cases. Seven eyes did not meet the success criteria: six eyes had a further increase in IOP and one eye showed intraocular hypotension.

CONCLUSION

The CPC‑M represents a good, inexpensive, and easily accessible treatment option for advanced glaucoma in order to reduce the likelihood of blindness in a low-income setting.

摘要

背景

青光眼是全球不可逆性失明的主要原因。坦桑尼亚农村地区青光眼患病率尤其高。贫困和眼科基础设施不足增加了青光眼治疗的难度。

目的

由于眼药水或手术治疗的可及性有限,本研究探讨了微脉冲技术经巩膜睫状体光凝术(CPC-M)在晚期青光眼中的有效性。

材料与方法

我们纳入了35例晚期青光眼成年患者的50只眼睛,这些眼睛具有青光眼典型的视乳头凹陷,杯盘比(CDR)≥0.9,无论青光眼类型如何。治疗前平均眼压(IOP)为34 mmHg(±14 mmHg)。手术在球后麻醉下使用A.R.C. FOX 810二极管激光(德国纽伦堡A.R.C. Laser公司;平均能量127 J±10 J)进行。

结果

眼压在6至21 mmHg之间或眼压降低至少初始值的20%被定义为成功。治疗3个月后,71%的重新评估眼睛(n = 21)达到成功标准,平均眼压为19 mmHg(±13 mmHg)。术后9个月(n = 20)平均眼压为18 mmHg(±10 mmHg),65%的病例达到成功标准。7只眼睛未达到成功标准:6只眼睛眼压进一步升高;1只眼睛出现眼内低血压。

结论

CPC-M是晚期青光眼一种良好、廉价且易于获得的治疗选择,有助于在低收入环境中降低失明可能性。

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