Rev Sci Tech. 2022 May;41(1):82-90. doi: 10.20506/rst.41.1.3305.
Drosophila melanogaster has been a model organism for experimental research for more than a century, and the knowledge and associated genetic technologies accumulated around this species make it extremely important to contemporary biomedical research. A large international community of highly collaborative scientists investigate a remarkable diversity of biological problems using genetically characterised strains of Drosophila, and frequently exchange these strains across borders. Despite its importance to the study of fundamental biological processes and human disease-related cellular mechanisms, and the fact that it presents minimal health, agricultural or environmental risks, Drosophila can be difficult to import. The authors argue that streamlined regulations and practices would benefit biomedical research by lowering costs and increasing efficiencies.
黑腹果蝇作为一个多世纪的实验研究模式生物,其相关的知识和遗传技术对当代生物医学研究极其重要。一个由高度协作的国际科学家群体组成的大型社区使用经过基因特征鉴定的黑腹果蝇品系来研究种类繁多的生物学问题,并经常在国界之外交换这些品系。尽管黑腹果蝇对基础生物过程和与人类疾病相关的细胞机制的研究很重要,而且它带来的健康、农业或环境风险极小,但它的进口可能很困难。作者认为,简化法规和实践将通过降低成本和提高效率使生物医学研究受益。