Cay Serkan, Kara Meryem, Ozcan Firat, Ozeke Ozcan, Korkmaz Ahmet, Cetin Hande, Aksu Tolga, Topaloglu Serkan
Division of Arrhythmia and Electrophysiology, Department of Cardiology, University of Health Sciences, Yuksek Ihtisas Cardiovascular Building, Ankara City Hospital, Ankara, Turkey.
Department of Electrophysiology, Yeditepe University Hospital, Istanbul, Turkey.
J Interv Card Electrophysiol. 2022 Dec;65(3):701-710. doi: 10.1007/s10840-022-01328-4. Epub 2022 Aug 4.
Several clinical risk factors and scoring systems have been proposed to predict arrhythmia recurrence after atrial fibrillation (AF) ablation. We sought to determine the ability of a new score to predict atrial arrhythmia recurrence after cryoballoon (CB) ablation of AF and whether the new score shows superior efficiency compared to previously offered scores.
A total of 419 patients with paroxysmal AF who underwent their first CB ablation were included. Baseline clinical variables were analyzed, and independent predictors of recurrence at 12 months were used to develop the PATCH score. The predictive capability of the new score was calculated and compared with the currently available risk scores.
Chronic obstructive pulmonary disease, left atrial dilatation, transient ischemic attack or stroke, congestive heart failure, and hypertension were independent predictors of recurrence. The PATCH score which was developed from these variables had a better clinical predictive capability of arrhythmia recurrence compared to HATCH and CHADS-VASc scores. With increasing PATCH score and score severity (low, score of 0; moderate, score of 1-2; and high, score of ≥ 3), the proportion of patients with recurrence was increased from 7% (score = 0, severity = low) to 59% (score ≥ 3, severity = high).
The PATCH score may help to identify patients who are likely benefited most from CB ablation of paroxysmal AF and who should be monitored more closely for arrhythmia recurrence at 12 months.
已经提出了几种临床风险因素和评分系统来预测心房颤动(AF)消融术后心律失常的复发。我们试图确定一种新的评分系统预测冷冻球囊(CB)消融AF术后房性心律失常复发的能力,以及该新评分系统与之前的评分系统相比是否具有更高的效率。
共纳入419例首次接受CB消融的阵发性AF患者。分析基线临床变量,并将12个月时复发的独立预测因素用于制定PATCH评分。计算新评分的预测能力,并与现有的风险评分进行比较。
慢性阻塞性肺疾病、左心房扩大、短暂性脑缺血发作或中风、充血性心力衰竭和高血压是复发的独立预测因素。与HATCH和CHADS-VASc评分相比,由这些变量制定的PATCH评分对心律失常复发具有更好的临床预测能力。随着PATCH评分及评分严重程度增加(低,评分为0;中度,评分为1-2;高,评分为≥3),复发患者比例从7%(评分为0,严重程度为低)增至59%(评分≥3,严重程度为高)。
PATCH评分可能有助于识别那些可能从阵发性AF的CB消融中获益最大的患者,以及那些在12个月时应更密切监测心律失常复发的患者。