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影响新生儿危殆事件的母体因素分析:一家三级医疗中心的经验

Analysis of Maternal Factors Impacting Neonatal Near Miss (NNM) Events: A Tertiary Centre Experience.

作者信息

Parulekar Maitreyee, Thakur Harshada, Samant Padmaja

机构信息

Minimally Invasive Gynecologic Surgery, Oyster Hospital, Goregaon, Mumbai India.

Department of Obstetrics and Gynaecology, Seth G.S Medical College and K.E.M Hospital, Parel, Mumbai India.

出版信息

J Obstet Gynaecol India. 2022 Aug;72(Suppl 1):75-82. doi: 10.1007/s13224-021-01554-2. Epub 2021 Sep 8.

DOI:10.1007/s13224-021-01554-2
PMID:35928059
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9343503/
Abstract

OBJECTIVE

To find out the incidence of neonatal near miss (NNM) cases in comparison with the neonatal deaths and to study the different antenatal and intrapartum maternal variables and system-related delays influencing these events.

METHODOLOGY

This is a descriptive retrospective study conducted over a year (2018-2019) at a tertiary referral hospital in India, where NNM cases were selected as per 'pragmatic criteria', and detailed maternal and neonatal biological variables and near miss indicators were procured from the medical record books and analysed.

RESULTS

Out of 6383 live births and 231 neonatal deaths in the hospital during the study period, 810 NNM cases were identified born to 710 mothers, i.e. 3.5 cases for each neonatal death. Birth weight and gestational age in combination contributed to the maximum number of cases-383 (47.28%). The most common reason for referral was threatened pre-term/PPROM with non-availability of NICU-197 cases (38.3%) out of 514 referrals. Out of 710 mothers, 529 (74.5%) had at least one comorbidity at the time of presentation. The most common comorbidity was anaemia in 267 women followed by hypertensive disorder of pregnancy-in 251 cases. Primary delay contributed to 54% of all delays in the study.

CONCLUSION

NNM can be used as an effective tool for quality control and audits to effectively reduce maternal and neonatal morbidity and mortality but needs more research to establish a standardized definition and criteria for selection of cases.

摘要

目的

查明新生儿危殆病例(NNM)的发生率,并与新生儿死亡情况进行比较,同时研究影响这些事件的不同产前和产时母体变量以及与系统相关的延误情况。

方法

这是一项在印度一家三级转诊医院进行的为期一年(2018 - 2019年)的描述性回顾性研究,按照“实用标准”选择NNM病例,并从病历中获取详细的母体和新生儿生物学变量以及危殆指标进行分析。

结果

在研究期间,该医院6383例活产中有231例新生儿死亡,共识别出810例NNM病例,其母亲为710人,即每例新生儿死亡对应3.5例NNM病例。出生体重和孕周共同导致的病例数最多,为383例(47.28%)。转诊的最常见原因是早产/未足月胎膜早破且无新生儿重症监护病房(NICU),在514例转诊病例中有197例(38.3%)。在710名母亲中,529名(74.5%)在就诊时有至少一种合并症。最常见的合并症是267名女性患贫血,其次是251例妊娠高血压疾病。在本研究中,主要延误占所有延误的54%。

结论

NNM可作为质量控制和审核的有效工具,以有效降低孕产妇和新生儿的发病率和死亡率,但需要更多研究来建立病例选择的标准化定义和标准。

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本文引用的文献

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Maternal near miss determinants at a maternity hospital for high-risk pregnancy in northeastern Brazil: a prospective study.巴西东北部一家高危妊娠妇产医院产妇near miss 决定因素的前瞻性研究。
BMC Pregnancy Childbirth. 2019 Aug 1;19(1):271. doi: 10.1186/s12884-019-2381-9.
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Non-obstetric causes of severe maternal complications: a secondary analysis of the Nigeria Near-miss and Maternal Death Survey.非产科原因导致的严重产妇并发症:对尼日利亚接近发生和孕产妇死亡调查的二次分析。
BJOG. 2019 Jun;126 Suppl 3:41-48. doi: 10.1111/1471-0528.15623. Epub 2019 Mar 21.
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A Call for Eminence Obstetrics Care by Way of "Neonatal Near Miss" Events (NNM): A Hospital-Based Case-Control Study.通过“新生儿近距离脱险”事件(NNM)呼吁卓越的产科护理:一项基于医院的病例对照研究。
J Obstet Gynaecol India. 2019 Feb;69(1):50-55. doi: 10.1007/s13224-018-1093-9. Epub 2018 Feb 14.
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Neonatal near miss determinants at a maternity hospital for high-risk pregnancy in Northeastern Brazil: a prospective study.巴西东北部一家高危妊娠产妇医院的新生儿接近错失决定因素:一项前瞻性研究。
BMC Pregnancy Childbirth. 2018 Oct 12;18(1):401. doi: 10.1186/s12884-018-2020-x.
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Pragmatic criteria of the definition of neonatal near miss: a comparative study.新生儿近死亡定义的实用标准:一项比较研究。
Rev Saude Publica. 2017 Dec 4;51:111. doi: 10.11606/S1518-8787.2017051006587.
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Neonatal Near Miss: the need for a standard definition and appropriate criteria and the rationale for a prospective surveillance system.新生儿近危事件:对标准定义、适当标准的需求以及建立前瞻性监测系统的基本原理。
Clinics (Sao Paulo). 2015 Dec;70(12):820-6. doi: 10.6061/clinics/2015(12)10.
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Neonatal near miss: a systematic review.新生儿濒临死亡病例:一项系统综述
BMC Pregnancy Childbirth. 2015 Dec 1;15:320. doi: 10.1186/s12884-015-0758-y.
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Still births, neonatal deaths and neonatal near miss cases attributable to severe obstetric complications: a prospective cohort study in two referral hospitals in Uganda.严重产科并发症所致死产、新生儿死亡及新生儿濒临死亡病例:乌干达两家转诊医院的前瞻性队列研究
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