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向颈部肌肉注射肉毒杆菌后齿状突后假瘤的消退

Regression of retro-odontoid pseudotumor following botulinum injection into cervical muscles.

作者信息

Kawanishi Masahiro, Tanaka Hidekazu, Ito Yutaka, Yamada Makoto, Yokoyama Kunio, Ikeda Naokado, Sugie Akira

机构信息

Department of Neurosurgery, Takeda General Hospital, Kyoto City, Kyoto, Japan.

出版信息

Surg Neurol Int. 2022 Jul 22;13:321. doi: 10.25259/SNI_606_2022. eCollection 2022.

DOI:10.25259/SNI_606_2022
PMID:35928316
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9345127/
Abstract

BACKGROUND

Posterior fixation of C1/2 has become more commonly performed to treat retro-odontoid pseudotumor (ROP). Here, we report a 60-year-old female with cervical dystonia (CD), whose ROP regressed and whose quadriparesis improved after a series of cervical intramuscular botulinum injections.

CASE DESCRIPTION

A 60-year-old female with 30 years of CD newly presented with a progressive quadriparesis. When the MRI showed ROP compression the cervical spinal cord, she refused surgery and underwent multiple cervical muscular botulinum injections over the next 2 years. Following these injections, the patient's quadriparesis improved as the ROP regressed on subsequent MR studies.

CONCLUSION

Over a 2-year period, multiple cervical botulinum injections caused regression of a retro-odontoid cervical pseudotumor improvement in the patient's quadriparesis.

摘要

背景

C1/2后路固定术已越来越常用于治疗齿突后假性肿瘤（ROP）。在此，我们报告一名60岁患有颈部肌张力障碍（CD）的女性，其ROP在一系列颈部肌肉注射肉毒杆菌毒素后消退，四肢瘫痪症状改善。

病例描述

一名患有30年CD的60岁女性新近出现进行性四肢瘫痪。当MRI显示ROP压迫颈脊髓时，她拒绝手术，并在接下来的2年里接受了多次颈部肌肉肉毒杆菌毒素注射。在这些注射后，随着ROP在后续MR研究中消退，患者的四肢瘫痪症状得到改善。

结论

在2年的时间里，多次颈部肉毒杆菌毒素注射导致齿突后颈部假性肿瘤消退，患者的四肢瘫痪症状得到改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80ee/9345127/490f0214774e/SNI-13-321-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80ee/9345127/52aa4db08566/SNI-13-321-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80ee/9345127/490f0214774e/SNI-13-321-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80ee/9345127/52aa4db08566/SNI-13-321-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80ee/9345127/490f0214774e/SNI-13-321-g002.jpg

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本文引用的文献

1
Retro-Odontoid and Retro-C2 Body Pseudotumor, Pannus, and/or Cyst. A Study Based on Analysis of 63 Cases.寰枢椎后缘及 C2 椎体后缘假瘤、滑膜、和/或囊肿。基于 63 例分析的研究。
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World Neurosurg. 2021 Feb;146:e1287-e1292. doi: 10.1016/j.wneu.2020.11.153. Epub 2020 Dec 4.
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Regression of Retro-odontoid Pseudotumor Using External Orthosis without Atlantoaxial Fusion: A Case Report.
使用外部矫形器无需寰枢椎融合治疗齿突后假瘤消退：一例报告
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