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关于筛查测试的研究

Research studies on screening tests.

作者信息

Aggarwal Rakesh, Ranganathan Priya, Pramesh C S

机构信息

Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Department of Anaesthesiology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, Maharashtra, India.

出版信息

Perspect Clin Res. 2022 Jul-Sep;13(3):168-171. doi: 10.4103/picr.picr_111_22. Epub 2022 Jun 30.

DOI:10.4103/picr.picr_111_22
PMID:35928637
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9345258/
Abstract

Screening tests are done to diagnose asymptomatic disease in apparently healthy people with the aim to reduce mortality and morbidity from the disease. Certain criteria need to be fulfilled before we adopt population-level screening for any disease. Several biases exist in evaluating screening studies, and the ideal study design would be a randomized trial with hard endpoints such as mortality and morbidity.

摘要

筛查测试是为了在看似健康的人群中诊断无症状疾病，目的是降低该疾病的死亡率和发病率。在我们对任何疾病采用人群水平的筛查之前，需要满足某些标准。在评估筛查研究时存在几种偏倚，理想的研究设计是采用具有死亡率和发病率等硬终点的随机试验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e45e/9345258/2783bfd5a2e9/PCR-13-168-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e45e/9345258/db5ea24c2b51/PCR-13-168-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e45e/9345258/2783bfd5a2e9/PCR-13-168-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e45e/9345258/db5ea24c2b51/PCR-13-168-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e45e/9345258/2783bfd5a2e9/PCR-13-168-g002.jpg

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本文引用的文献

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Effect of screening by clinical breast examination on breast cancer incidence and mortality after 20 years: prospective, cluster randomised controlled trial in Mumbai.临床乳房检查筛查对 20 年后乳腺癌发病率和死亡率的影响：孟买前瞻性、整群随机对照试验。
BMJ. 2021 Feb 24;372:n256. doi: 10.1136/bmj.n256.
2
Understanding diagnostic tests - Part 3: Receiver operating characteristic curves.理解诊断测试——第3部分：受试者工作特征曲线
Perspect Clin Res. 2018 Jul-Sep;9(3):145-148. doi: 10.4103/picr.PICR_87_18.
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Understanding the properties of diagnostic tests - Part 2: Likelihood ratios.
基于文献和经验的台湾地区急性术后眼内炎和内源性眼内炎共识
Ophthalmol Ther. 2024 Jan;13(1):1-19. doi: 10.1007/s40123-023-00835-5. Epub 2023 Nov 7.
了解诊断试验的特性——第2部分：似然比。
Perspect Clin Res. 2018 Apr-Jun;9(2):99-102. doi: 10.4103/picr.PICR_41_18.
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Common pitfalls in statistical analysis: Understanding the properties of diagnostic tests - Part 1.统计分析中的常见陷阱：理解诊断试验的特性 - 第1部分。
Perspect Clin Res. 2018 Jan-Mar;9(1):40-43. doi: 10.4103/picr.PICR_170_17.
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Screening for Thyroid Cancer: US Preventive Services Task Force Recommendation Statement.甲状腺癌筛查：美国预防服务工作组推荐声明。
JAMA. 2017 May 9;317(18):1882-1887. doi: 10.1001/jama.2017.4011.
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Flawed inferences about screening mammography's benefit based on observational data.基于观察性数据对乳腺钼靶筛查益处的错误推断。
J Clin Oncol. 2009 Feb 1;27(4):639-40; author reply 641-2. doi: 10.1200/JCO.2008.17.9341. Epub 2008 Dec 15.