Rahman Md Mizanur, Munia Ashfia Tasnim, Sikdar K M Yasif Kayes, Sarkar Md Raihan
Department of Pharmacy, University of Dhaka, Dhaka, Bangladesh.
Institute of Statistical Research and Training, University of Dhaka, Dhaka, Bangladesh.
Perspect Clin Res. 2022 Jul-Sep;13(3):161-167. doi: 10.4103/picr.PICR_245_20. Epub 2021 Mar 26.
The rational prescription leads to a healthy and good-quality life of a patient. Irrational, inappropriate, and unnecessary prescriptions are major therapeutic issues in Bangladesh, which can cause severe consequences.
This cross-sectional study was conducted to evaluate the prescription patterns and errors as well as to review the most frequently prescribed drug classes among outpatients at a secondary hospital in Pabna, a district of Bangladesh.
A total of 400 prescriptions were reviewed from March 2019 to May 2019. In this study, statistical data analysis was implemented by IBM SPSS Statistics V22 and data revealed in frequencies, mean, and percentage. Spearman's rank correlation coefficient was calculated to show the correlation between bivariate coded variables.
The results revealed that majority of the prescription were prescribed for females (73.5%) where proton-pump inhibitors (PPIs), analgesics, vitamins, and single antibiotics were most frequently prescribed medicine for the female patients compared to male patients. Almost half of the collected prescription contained four medicines (47%). Maximum number of prescriptions contained two (30.5%) essential drugs and among 1402 medicines of 400 prescriptions, antiulcerants were most frequently prescribed medicine (23.32%) where esomeprazole was highly prescribed generic drug (44.75%). Moreover, Spearman's rank correlation coefficient suggested that PPIs and analgesics were frequently prescribed medicines at a time for the patients (0.182). According to the age group, the study also got some significant variations in prescribing pattern. However, most common prescription errors were prescriber's name not mentioned (100%), diagnosis not mentioned (96.75%), dose not indicated (15.41%), and wrong drug name (0.36%).
Findings of the current study represent the existing prescribing trends of different therapeutic classes of drugs and common prescription errors in a secondary health facility of Bangladesh. From this study, it is observed that physicians prescribed rationally in some cases but need to ensure rationality in all prescriptions. Continuous monitoring of drug use, development of prescribing guidelines, and training are recommended to ensure and implement good-quality prescribing practices for promoting the rational and cost-effective use of drugs.
合理用药可使患者过上健康且高质量的生活。不合理、不恰当及不必要的用药处方是孟加拉国的主要治疗问题，可能会导致严重后果。
本横断面研究旨在评估一家位于孟加拉国帕布纳区的二级医院门诊患者的处方模式与用药错误情况，并回顾最常开具的药物类别。
对2019年3月至2019年5月期间的400份处方进行了回顾。在本研究中，采用IBM SPSS Statistics V22进行统计数据分析，并以频率、均值和百分比的形式呈现数据。计算斯皮尔曼等级相关系数以显示双变量编码变量之间的相关性。
结果显示，大多数处方是为女性开具的（73.5%），与男性患者相比，质子泵抑制剂（PPI）、镇痛药、维生素和单一抗生素是女性患者最常开具的药物。几乎一半的收集到的处方包含四种药物（47%）。最大数量的处方包含两种（30.5%）基本药物，在400份处方的1402种药物中，抗溃疡药是最常开具的药物（23.32%），其中埃索美拉唑是开具频率最高的通用名药物（44.75%）。此外，斯皮尔曼等级相关系数表明，PPI和镇痛药是患者同时经常开具的药物（0.182）。根据年龄组，该研究在处方模式上也有一些显著差异。然而，最常见的处方错误是未提及开处方者姓名（100%）、未提及诊断（96.75%）、未标明剂量（15.41%）和药物名称错误（0.36%）。
本研究结果反映了孟加拉国一家二级医疗机构中不同治疗类别的药物现有的处方趋势和常见的处方错误。从本研究中可以观察到，医生在某些情况下合理用药，但需要确保所有处方的合理性。建议持续监测药物使用情况、制定处方指南并进行培训，以确保并实施高质量的处方实践，促进药物的合理和成本效益使用。
