Ben Kridis Wala, Lajnef Mayssa, Fki Ameni, Belaid Laila, Khanfir Afef
Department of Medical Oncology Habib Bourguiba Hospital University of Sfax Sfax Tunisia.
Department of Pathology Tahar Sfar Hospital Mahdia Sfax Tunisia.
JGH Open. 2022 Jul 7;6(8):587-589. doi: 10.1002/jgh3.12784. eCollection 2022 Aug.
Invasive lobular carcinoma is the second-most-common subtype of breast cancer. It is characterized by a different metastatic pattern with a propensity to metastasize to pleura, peritoneum, gastrointestinal tract, and ovary. We report a woman with known metastatic disease outside the gastrointestinal tract who had endoscopy and colonoscopy for gastrointestinal symptoms. Extensive metastases were found in the stomach and colon with a diffuse infiltration of signet ring-like cells at histology and immunohistochemical findings consistent with breast carcinoma. To the best of our knowledge, this is the first report of such a case from Africa.
浸润性小叶癌是乳腺癌的第二常见亚型。其特点是转移模式不同，倾向于转移至胸膜、腹膜、胃肠道和卵巢。我们报告一名已知有胃肠道外转移疾病的女性，因胃肠道症状接受了内镜检查和结肠镜检查。在胃和结肠发现广泛转移，组织学检查显示印戒样细胞弥漫浸润，免疫组化结果符合乳腺癌。据我们所知，这是来自非洲的此类病例的首例报告。
