Ives T J, Bentz E J, Gwyther R E
Arch Intern Med. 1987 Jun;147(6):1117-20.
Admissions to a family medicine inpatient service were monitored retrospectively over a one-year period to determine the incidence of drug-related hospitalizations. Of the 293 admissions, 45 (15.4%) were identified as drug related; in 29 admissions (9.9%), a drug-related problem was identified as the primary cause of hospitalization. The two patient characteristics associated with a drug-related admission (DRA) were marital status (divorced) and age (older patients). The two most common types of DRAs were adverse drug reactions (17/45, 37.8%) and drug abuse (14/45, 31.1%), with alcohol being the most commonly abused agent. Adverse drug reactions were most commonly implicated in DRAs for patients over 70 years old, with drug abuse more evenly distributed among age groups. Educational programs that incorporate pharmacoepidemiologic strategies into all health care disciplines are necessary to address this public health issue.
对一家家庭医学住院服务机构在一年期间的入院情况进行了回顾性监测，以确定与药物相关的住院发生率。在293例入院病例中，45例（15.4%）被确定为与药物相关；在29例（9.9%）中，药物相关问题被确定为住院的主要原因。与药物相关入院（DRA）相关的两个患者特征是婚姻状况（离婚）和年龄（老年患者）。两种最常见的DRA类型是药物不良反应（17/45，37.8%）和药物滥用（14/45，31.1%），酒精是最常被滥用的药物。药物不良反应在70岁以上患者的DRA中最常见，而药物滥用在各年龄组中分布更为均匀。将药物流行病学策略纳入所有医疗保健学科的教育项目对于解决这一公共卫生问题是必要的。
