Al-Olah Yosef H, Al Thiab Khalifa M
Pharmaceutical Care Department, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Ann Saudi Med. 2008 Nov-Dec;28(6):426-9. doi: 10.5144/0256-4947.2008.426.
Hospital admissions due to drug-related problems (DRPs) have been studied internationally, but local data are limited. Therefore, we undertook a prospective, observational study of all admmissions through the emergency department (ED) at a tertiary referral hospital in Saudi Arabia to determine the incidence of admissions through the ED due to DRPs, types of DRPs, length of stay (LOS) in the hospital after ED admissions due to DRPs, and assessment of preventability of admissions due to DRPs.
All admissions through the ED over a period of 28 consecutive days were evaluated to determine if they were due to definite or possible DRPs. Data was collected on a daily basis for each admission over the previous 24 hours. Each incident was assessed by three investigators.
Of 557 patients admitted through the ED, 82 (14.7%) admissions were due to DRP (53 definite, 29 possible). The most common types of DRP were failure to receive medication in 25 cases (47.2%), an adverse drug reaction in 13 cases (24.5%), and drug overdose in 6 cases (11.3%). In the definite DRP group, 83.0% were definitely preventable, 3.8% were possibly preventable and 13.2% were definitely non-preventable.
DRPs are a serious and costly issue facing health care professionals and health care systems. Most admissions due to DRPs are avoidable.
药物相关问题(DRP)导致的住院情况已在国际上得到研究,但本地数据有限。因此,我们在沙特阿拉伯一家三级转诊医院对通过急诊科(ED)的所有住院患者进行了一项前瞻性观察研究,以确定因DRP通过ED住院的发生率、DRP的类型、因DRP通过ED住院后在医院的住院时间(LOS),以及对因DRP住院的可预防性进行评估。
对连续28天内通过ED的所有住院患者进行评估,以确定他们是否因明确或可能的DRP而住院。每天收集前24小时内每次住院的数据。每个事件由三名研究人员进行评估。
在通过ED住院的557名患者中,82例(14.7%)住院是由于DRP(53例明确,29例可能)。最常见的DRP类型是25例(47.2%)未接受药物治疗、13例(24.5%)药物不良反应和6例(11.3%)药物过量。在明确的DRP组中,83.0%肯定是可预防的,3.8%可能是可预防的,13.2%肯定是不可预防的。
DRP是医疗保健专业人员和医疗保健系统面临的一个严重且代价高昂的问题。大多数因DRP导致的住院是可以避免的。