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孕妇接种疫苗后 SARS-CoV-2 母传抗体垂直传递至新生儿和婴幼儿的定量分析。

Quantitative Analysis of Vertical Transmission of Maternal SARS-CoV-2 Antibodies to Neonates and Young Infants Following Immunization During Pregnancy.

机构信息

Department of Pediatrics A, Schneider Children's Medical Center, Petah Tikva, Israel.

Adelson School of Medicine, Ariel University, Ariel, Israel.

出版信息

J Pediatric Infect Dis Soc. 2022 Dec 5;11(11):506-509. doi: 10.1093/jpids/piac065.

DOI:10.1093/jpids/piac065
PMID:35929547
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9384628/
Abstract

Serum antibody levels to SARS-CoV-2 in infants born to mothers who had received 2 doses of the BNT2b2 vaccine during pregnancy correlated positively with increasing gestational age at vaccination (P < .01) and negatively with increasing time from vaccination (P < .01), with a significant drop in infants aged >60 days (P = .045).

摘要

母亲在怀孕期间接种 2 剂 BNT2b2 疫苗后，婴儿血清中针对 SARS-CoV-2 的抗体水平与接种时的胎龄增加呈正相关（P <.01），与接种后时间的延长呈负相关（P <.01），60 天以上婴儿的抗体水平显著下降（P =.045）。

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