新型冠状病毒肺炎（COVID-19）急性后遗症（PASC）中的呼吸问题综述及肺康复的潜在益处

A Review of Respiratory Post-Acute Sequelae of COVID-19 (PASC) and the Potential Benefits of Pulmonary Rehabilitation.

作者信息

Simon Michael, Simmons James E

机构信息

Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Alpert Medical School of Brown University, Providence, Rhode Island.

Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Alpert Medical School of Brown University, Providence, Rhode Island; The Miriam Hospital Center for Cardiac, Pulmonary and Vascular Fitness, Pulmonary Rehabilitation Program.

出版信息

R I Med J (2013). 2022 Sep 1;105(7):11-15.

PMID:35930484

Abstract

With the SARS-CoV-2 pandemic continuing into its third year, the number of patients who survive acute COVID-19 infection but go on to develop long-term symptoms is increasing daily. Those individuals who experience one or more of a variety of persistent symptoms post-COVID-19 are now diagnosed with the syndrome called post-acute sequelae of COVID-19 (PASC), often colloquially called "Long COVID." This article discusses relevant research and current hypotheses regarding the pathophysiology and management of respiratory symptoms of PASC, in order to provide primary care physicians with context for management of this heterogeneous population. We focus on the growing body of research that supports the use of pulmonary rehabilitation for patients with PASC to improve symptoms and quality of life.

摘要

随着新冠疫情进入第三年，急性新冠病毒感染后存活但出现长期症状的患者数量与日俱增。那些在新冠病毒感染后经历多种持续症状中一种或多种的个体，现在被诊断为患有新冠后急性后遗症（PASC）综合征，通常通俗地称为“长新冠”。本文讨论了有关PASC病理生理学及呼吸症状管理的相关研究和当前假说，以便为基层医疗医生管理这一异质性群体提供背景信息。我们重点关注越来越多的研究，这些研究支持对PASC患者使用肺康复治疗以改善症状和生活质量。