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在第 36 或 37 孕周的常规检查中,为初产妇开发一种用于预测分娩停止的预测模型:一项回顾性队列研究。

The development of a prediction model for arrest of labour to be used at regular check-ups, during 36 or 37 gestational weeks, for primiparas: a retrospective cohort study.

机构信息

Department of Preventive Services, School of Public Health in the Graduate School of Medicine, Kyoto University, Yoshida-honmachi, Sakyo-ku, Kyoto, 606-8501, Japan.

Kyoto Min-iren Chuo Hospital, 2-1 Uzumasa Tsuchimoto-cho, Ukyo-ku, Kyoto, 616-8147, Japan.

出版信息

Arch Gynecol Obstet. 2023 Aug;308(2):453-461. doi: 10.1007/s00404-022-06710-1. Epub 2022 Aug 6.

DOI:10.1007/s00404-022-06710-1
PMID:35931901
Abstract

PURPOSE

An emergency caesarean section (CS) has more complications than a planned CS. The arrest of labour is a major indication for an emergency CS. This study aimed to develop a prediction model for the arrest of labour to be used in regular check-ups at 36 or 37 gestational weeks for primiparas.

METHODS

This was a retrospective cohort study conducted at a single institution in Japan using data from January 2007 to December 2013. Primiparas attending regular check-ups during 36 or 37 gestational weeks, with live single foetuses in a cephalic presentation were included. The outcome was the incidence of labour arrest. Candidate predictors included 25 maternal and foetal findings. We developed a prediction model using logistic regression analysis with stepwise selection. A score was assigned to each predictor of the final model based on their respective β coefficients.

RESULTS

A total of 739 women were included in the analysis. Arrest of labour was diagnosed in 47 women (6.4%), and all of them delivered by emergency CS. The predictors in the final model were a Bishop score ≤ 1, maternal height ≤ 154 cm, foetal biparietal diameter ≥ 91 mm, pre-pregnancy weight ≥ 54 kg, maternal haemoglobin concentration ≥ 11.0 g/dl, and amniotic fluid index ≥ 13. The area under the receiver operating characteristic curve was 0.783.

CONCLUSION

We have developed the first model to predict arrested labour before its onset. Although this model requires validation using external samples, it will help clinicians and pregnant women to control gestational conditions and make decisions regarding planned CS.

摘要

目的

紧急剖宫产(CS)比计划性 CS 并发症更多。产程阻滞是紧急 CS 的主要指征。本研究旨在为初产妇在 36 或 37 孕周的常规检查中开发一种用于预测产程阻滞的模型。

方法

这是一项在日本单中心进行的回顾性队列研究,使用了 2007 年 1 月至 2013 年 12 月的数据。纳入在 36 或 37 孕周进行常规检查、单胎头位活产的初产妇。结局是产程阻滞的发生率。候选预测因子包括 25 项母体和胎儿指标。我们使用逐步选择的逻辑回归分析建立预测模型。根据最终模型中每个预测因子的相应β系数,为每个预测因子分配一个分数。

结果

共有 739 名妇女纳入分析。47 名妇女(6.4%)诊断为产程阻滞,均行急诊 CS 分娩。最终模型中的预测因子包括 Bishop 评分≤1、产妇身高≤154cm、胎儿双顶径≥91mm、孕前体重≥54kg、产妇血红蛋白浓度≥11.0g/dl 和羊水指数≥13。受试者工作特征曲线下面积为 0.783。

结论

我们已经开发出第一个预测产程阻滞的模型。尽管该模型需要使用外部样本进行验证,但它将有助于临床医生和孕妇控制妊娠情况并做出关于计划性 CS 的决策。

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本文引用的文献

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Sonographic risk assessment for an unplanned operative delivery: a prospective study.计划外剖宫产的超声风险评估:一项前瞻性研究。
Arch Gynecol Obstet. 2022 Nov;306(5):1469-1475. doi: 10.1007/s00404-022-06413-7. Epub 2022 Feb 2.
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Combination of early pushing with extended second stage increases the rates of spontaneous vaginal deliveries, but might be associated with adverse maternal and neonatal outcomes.早期推挤与第二产程延长相结合可增加自然分娩率,但可能与母婴不良结局相关。
Arch Gynecol Obstet. 2022 Jan;305(1):39-45. doi: 10.1007/s00404-021-06111-w. Epub 2021 Jun 1.
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Quantification of Posterior Risk Related to Intrapartum FIGO 2015 Criteria for Cardiotocography in the Second Stage of Labor.
第二产程中应用 FIGO 2015 胎心监护标准的相关风险的量化评估。
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Association between Maternal Weight Indicators and Iron Deficiency Anemia during Pregnancy: A Cohort Study.母亲体重指标与妊娠期缺铁性贫血的关联:一项队列研究。
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Ultrasonographic estimation of fetal weight: development of new model and assessment of performance of previous models.超声估测胎儿体重:新模型的建立及对旧模型效能的评估。
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