Kodícek M, Mircevová L, Marík T
Biomed Biochim Acta. 1987;46(2-3):S103-7.
Factors influencing an increase of glucose consumption in erythrocytes under mechanical stress were studied. Under the shear stress of 2000-5000 s-1 the glucose consumption goes up 20-50%. This effect disappears in protein-free media, in Ca2+-free media and in resealed red ghosts; in all these cases certain morphological deviations were observed in the stressed cells. These results confirm the vital role of energy-consuming contractile apparatus of erythrocyte membrane in restoration of the smooth biconcave shape after deformation.
研究了机械应力作用下影响红细胞葡萄糖消耗增加的因素。在2000 - 5000 s-1的剪切应力下,葡萄糖消耗量增加20 - 50%。这种效应在无蛋白培养基、无Ca2+培养基和重新封闭的红细胞影中消失;在所有这些情况下,在受应力的细胞中都观察到了某些形态学偏差。这些结果证实了红细胞膜耗能收缩装置在变形后恢复光滑双凹形中的重要作用。