Bernhardt I, Erdmann A, Vogel R, Glaser R
Biomed Biochim Acta. 1987;46(2-3):S36-40.
The rate constant of the Rb+(K+) efflux in isotonic NaCl solutions containing sucrose is increased when the NaCl concentration is reduced. When NaCl is replaced by Na-gluconate no change of the rate constant can be observed. The ionic strength of the solution is discussed as one factor influencing the Rb+(K+) efflux. The addition of furosemide (0.5 mM) inhibits the rate constant of the Rb+(K+) efflux in solutions of different ionic strength by about 50%. The increase of the rate constant in solutions of low ionic strength containing sucrose is interpreted as a stimulation of the chloride-dependent Na,K cotransport and the K,Cl cotransport.
在含有蔗糖的等渗氯化钠溶液中,当氯化钠浓度降低时,铷离子(钾离子)外流的速率常数会增加。当用葡萄糖酸钠替代氯化钠时,未观察到速率常数的变化。溶液的离子强度被视为影响铷离子(钾离子)外流的一个因素。添加呋塞米(0.5 mM)可使不同离子强度溶液中铷离子(钾离子)外流的速率常数降低约50%。在含有蔗糖的低离子强度溶液中速率常数的增加被解释为对氯离子依赖性钠钾协同转运和钾氯协同转运的刺激。