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一名年轻女性,发热、腹痛和嗜酸性粒细胞增多。

A young female with fever, abdominal pain and eosinophilia.

机构信息

Infectious Diseases Department, Sterling Hospital, Ahmedabad 380052, India.

Microbiology Department, Sterling Hospital, Ahmedabad 380052, India.

出版信息

Indian J Med Microbiol. 2022 Jul-Sep;40(3):449-450. doi: 10.1016/j.ijmmb.2022.07.012. Epub 2022 Aug 3.

DOI:10.1016/j.ijmmb.2022.07.012
PMID:35933240
Abstract

Fascioliasis has been reported from many countries across the globe. Acute phase of liver fluke is characterised by fever, abdominal pain and peripheral blood eosinophilia while the chronic phase is marked by chronic inflammation involving biliary tract. It is commonly diagnosed by a radiologist due to characteristic branching abscesses seen on CT scan, highly suggestive of liver fluke. Diagnosis is made by demonstration of eggs on direct microscopic examination of duodenal aspirate or bile. Screening of family members is recommended once diagnosis is has been made. Triclabendazole is the drug of choice for treatment.

摘要

肝片形吸虫病已在全球许多国家报告过。肝片形吸虫的急性期以发热、腹痛和外周血嗜酸性粒细胞增多为特征,而慢性期则以胆道慢性炎症为特征。由于 CT 扫描可见特征性分支脓肿,放射科医生通常可以诊断该病,高度提示肝片形吸虫病。通过直接镜检十二指肠抽吸物或胆汁中虫卵可作出诊断。一旦确诊,建议对家庭成员进行筛查。三氯苯达唑是治疗的首选药物。

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Human fascioliasis emergence in southern Asia: Complete nuclear rDNA spacer and mtDNA gene sequences prove Indian patient infection related to fluke hybridization in northeastern India and Bangladesh.南亚人体片形吸虫病的出现:完整的核核糖体DNA间隔区和线粒体DNA基因序列证明印度患者感染与印度东北部和孟加拉国的吸虫杂交有关。
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