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抑郁症患者中分离症状的流行情况及其相关因素。

Prevalence and correlates of dissociative symptoms among people with depression.

机构信息

Department of Social Work, Hong Kong Baptist University, Hong Kong; The Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong.

The Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong.

出版信息

J Psychiatr Res. 2022 Oct;154:132-138. doi: 10.1016/j.jpsychires.2022.07.054. Epub 2022 Jul 31.

Abstract

BACKGROUND

To improve the outcomes of depression treatment, personalized treatments that take individual needs into account are recommended. Recent research suggests that a subgroup of depressed people who suffer from co-occurring dissociation may be more likely to have encountered traumatic or stressful experiences and they may also have more psychosocial intervention needs.

METHODS

This study examined the prevalence and correlates of dissociative symptoms in an online convenience sample of people (N = 410) from 18 different countries/regions who reported clinically significant levels of depressive symptoms (indicated by Patient Health Questionnaire-9 score ≥10).

RESULTS

Over 60% of participants exhibited clinically significant levels of dissociative symptoms (indicated by a Multiscale Dissociation Inventory total score >66). Compared with those with low levels of dissociative symptoms, participants with high levels of dissociative symptoms reported more traumas, interpersonal stress, depression and trauma-related symptoms. Emotional constriction in particular had a weak but significant negative correlation with the level of perceived medication benefits.

LIMITATIONS

The use of an online convenience sample could limit the generalizability of our findings. Our cross-sectional data could not demonstrate causal relationships between the study variables.

CONCLUSIONS

The findings highlight a need for complex health interventions for depressed people with co-occurring dissociative symptoms, focusing not only on depressive symptoms but also addressing trauma and dissociation-related symptoms.

摘要

背景

为了改善抑郁治疗的效果,建议采用考虑个体需求的个性化治疗。最近的研究表明,同时存在共病解离的抑郁患者亚组可能更容易遇到创伤或压力事件,他们可能也有更多的心理社会干预需求。

方法

本研究在来自 18 个不同国家/地区的在线便利样本(N=410)中,调查了共病解离症状的发生率及其相关因素,这些人报告了具有临床意义的抑郁症状(患者健康问卷-9 评分≥10 分)。

结果

超过 60%的参与者表现出具有临床意义的解离症状(多尺度解离量表总分>66 分)。与解离症状水平较低的参与者相比,解离症状水平较高的参与者报告了更多的创伤、人际压力、抑郁和与创伤相关的症状。情感收缩与药物治疗效果感知之间呈弱但显著的负相关。

局限性

使用在线便利样本可能会限制我们发现的普遍性。我们的横断面数据不能证明研究变量之间的因果关系。

结论

研究结果强调了需要针对同时存在共病解离症状的抑郁患者进行复杂的健康干预,不仅要关注抑郁症状,还要解决与创伤和解离相关的症状。

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