Connelly D M, Harries E H, Taberner P V
Alcohol Alcohol. 1987;22(1):23-9.
Plasma glucose levels (PGL) in healthy non-alcoholic heavy drinkers of both sexes were significantly higher than in light drinkers following feeding or fasting. Female heavy drinkers showed significant glucose intolerance following a standard (75 g) glucose tolerance test. Acute alcohol consumption (0.4 g/kg orally) produced a larger fall in the PGL of heavy, compared with light, drinkers, although the rate of clearance of alcohol was similar in both groups. It is concluded that mild hyperglycaemia and glucose intolerance can occur in regular heavy drinkers who are otherwise clinically normal. It is suggested that previous drinking history is an important factor to be considered in assessing the metabolic response of non-alcoholics to acute alcohol consumption.
在进食或禁食后，健康的非酒精性重度饮酒的男女血浆葡萄糖水平（PGL）显著高于轻度饮酒者。在标准（75克）葡萄糖耐量试验后，女性重度饮酒者表现出明显的葡萄糖不耐受。与轻度饮酒者相比，急性饮酒（口服0.4克/千克）使重度饮酒者的PGL下降幅度更大，尽管两组酒精清除率相似。结论是，在临床上其他方面正常的经常重度饮酒者中可能会出现轻度高血糖和葡萄糖不耐受。建议在评估非酒精性者对急性饮酒的代谢反应时，既往饮酒史是一个需要考虑的重要因素。
