Sayre M R, Roberge R J, Evans T C
Am J Emerg Med. 1987 Jul;5(4):298-301. doi: 10.1016/0735-6757(87)90355-x.
Intracranial hematomas in patients with osteogenesis imperfecta rarely are reported despite an increased incidence of skull fractures. We present a case of a patient with osteogenesis imperfecta but without any history of trauma or chronic anticoagulation in whom a subdural hematoma occurred during hemodialysis. Despite operative intervention, the patient died. We could find no other cases in the medical literature of a patient with osteogenesis imperfecta who had an intracranial hematoma in the absence of a skull fracture. Patients with osteogenesis imperfecta may be at high risk for intracranial bleeding from coagulation abnormalities or otherwise trivial injuries.
尽管成骨不全患者颅骨骨折的发生率有所增加，但关于其颅内血肿的报道却很少。我们报告了一例成骨不全患者，该患者无任何外伤史或长期抗凝史，在血液透析期间发生了硬膜下血肿。尽管进行了手术干预，患者仍死亡。在医学文献中，我们未发现其他无颅骨骨折的成骨不全患者发生颅内血肿的病例。成骨不全患者可能因凝血异常或其他轻微损伤而有颅内出血的高风险。
