Department of Gastroenterology, The Fourth Hospital of Harbin Medical University, Harbin 150001, China.
Department of Histology and Embryology, Mudanjiang Medical University, Mudanjiang 157011, China.
Contrast Media Mol Imaging. 2022 Jul 19;2022:2279018. doi: 10.1155/2022/2279018. eCollection 2022.
The aim of this research was to investigate the predictive role of texture features in computed tomography (CT) images based on artificial intelligence (AI) algorithms for colorectal liver metastases (CRLM). A total of 150 patients with colorectal cancer who were admitted to the hospital were selected as the research objects and randomly divided into three groups with 50 cases in each group. The patients who were found to suffer from the CRLM in the initial examination were included in group A. Patients who were found with CRLM in the follow-up were assigned to group B (B1: metastasis within 0.5 years, 16 cases; B2: metastasis within 0.5-1.0 years, 17 cases; and B3: metastasis within 1.0-2.0 years, 17 cases). Patients without liver metastases during the initial examination and subsequent follow-up were designated as group C. Image textures were analyzed for patients in each group. The prediction accuracy, sensitivity, and specificity of CRLM in patients with six classifiers were calculated, based on which the receiver operator characteristic (ROC) curves were drawn. The results showed that the logistic regression (LR) classifier had the highest prediction accuracy, sensitivity, and specificity, showing the best prediction effect, followed by the linear discriminant (LD) classifier. The prediction accuracy, sensitivity, and specificity of the LR classifier were higher in group B1 and group B3, and the prediction effect was better than that in group B2. The texture features of CT images based on the AI algorithms showed a good prediction effect on CRLM and had a guiding significance for the early diagnosis and treatment of CRLM. In addition, the LR classifier showed the best prediction effect and high clinical value and can be popularized and applied.
本研究旨在探讨基于人工智能(AI)算法的 CT 图像纹理特征对结直肠癌肝转移(CRLM)的预测作用。选取我院收治的 150 例结直肠癌患者为研究对象,随机分为三组,每组 50 例。初诊时发现 CRLM 的患者纳入 A 组,随访时发现 CRLM 的患者分为 B 组(B1:转移时间在 0.5 年内,16 例;B2:转移时间在 0.5-1.0 年内,17 例;B3:转移时间在 1.0-2.0 年内,17 例)。初诊和后续随访均无肝转移的患者为 C 组。对每组患者的图像纹理进行分析。计算 6 种分类器对患者 CRLM 的预测准确率、敏感度和特异度,绘制受试者工作特征(ROC)曲线。结果显示,逻辑回归(LR)分类器预测准确率、敏感度和特异度最高,预测效果最佳,其次是线性判别(LD)分类器。LR 分类器在 B1 组和 B3 组中的预测准确率、敏感度和特异度均较高,预测效果优于 B2 组。基于 AI 算法的 CT 图像纹理特征对 CRLM 具有良好的预测效果,对 CRLM 的早期诊断和治疗具有指导意义。此外,LR 分类器预测效果最佳,具有较高的临床应用价值,可推广应用。