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转诊至精神科诊所的注意力缺陷多动障碍儿童阻塞性睡眠呼吸暂停高危患病率及其对生活质量的影响。

Prevalence of high-risk for obstructive sleep apnea in attention deficit hyperactivity disorder children referred to psychiatry clinic and impact on quality of life.

作者信息

Prajsuchanai Tipkamol, Tanphaichitr Archwin, Hosiri Tikumporn, Ungkanont Kitirat, Banhiran Wish, Vathanophas Vannipa, Gozal David

机构信息

Department of Otorhinolaryngology, Uthai Thani Hospital, Uthai Thani, Thailand.

Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Front Psychiatry. 2022 Jul 22;13:926153. doi: 10.3389/fpsyt.2022.926153. eCollection 2022.

Abstract

OBJECTIVES

To study the prevalence of high-risk obstructive sleep apnea (OSA) in attention deficit hyperactivity disorder (ADHD) children in a child and adolescent psychiatry clinic using the Thai version of the Pediatric Obstructive Sleep Apnea Screening Tool (POSAST) questionnaire. The secondary objective was to evaluate the quality of life and identify associated factors for high-risk OSA in ADHD children.

STUDY DESIGN

Prospective cross-sectional study.

MATERIAL AND METHOD

Caregivers of pediatric patients aged 5-18 years old and diagnosed with ADHD by child and adolescent psychiatrists were surveyed about their child's sleeping habits.

RESULTS

Two hundred and seventy-four subjects were included. The patients' mean age was 10.4 ± 2.6 years, and 82.8% were males. There were 30 children (10.9%) diagnosed with obesity, 46 (16.8%) with chronic rhinitis, and 9 (3.3%) with asthma. The median duration of ADHD symptoms was 22.1 months. The prevalence of high-risk OSA was 18.2% and was associated with significantly reduced quality of life (adjusted OR = 4.46, 95% CI: 2.26-8.81, < 0.001). A significant association between high-risk OSA and obesity also emerged (adjusted OR = 2.84, 95% CI: 1.17-6.88, = 0.021).

CONCLUSION

An elevated prevalence of high-risk OSA is present among Thai children with ADHD, and significantly impacts quality of life. A significant association between high-risk OSA and obesity is also detected in patients with ADHD. Therefore, screening for high-risk OSA in ADHD patients may likely facilitate early detection and treatment of OSA, and potentially prevent adverse consequences.

摘要

目的

使用泰语版的儿童阻塞性睡眠呼吸暂停筛查工具(POSAST)问卷,研究儿童和青少年精神病诊所中注意力缺陷多动障碍(ADHD)儿童的高危阻塞性睡眠呼吸暂停(OSA)患病率。次要目的是评估ADHD儿童的生活质量,并确定高危OSA的相关因素。

研究设计

前瞻性横断面研究。

材料与方法

对年龄在5 - 18岁、经儿童和青少年精神科医生诊断为ADHD的儿科患者的照顾者进行调查,了解其孩子的睡眠习惯。

结果

纳入274名受试者。患者的平均年龄为10.4±2.6岁,82.8%为男性。有30名儿童(10.9%)被诊断为肥胖,46名(16.8%)患有慢性鼻炎,9名(3.3%)患有哮喘。ADHD症状的中位持续时间为22.1个月。高危OSA的患病率为18.2%,并与生活质量显著降低相关(调整后的OR = 4.46,95%CI:2.26 - 8.81,<0.001)。高危OSA与肥胖之间也出现了显著关联(调整后的OR = 2.84,95%CI:1.17 - 6.88,= 0.021)。

结论

泰国ADHD儿童中高危OSA的患病率升高,且对生活质量有显著影响。在ADHD患者中还检测到高危OSA与肥胖之间存在显著关联。因此,对ADHD患者进行高危OSA筛查可能有助于早期发现和治疗OSA,并可能预防不良后果。

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