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适用于孕期的YEARS算法在疑似患有肺栓塞的妊娠及产后患者中安全识别行CT肺动脉造影患者的有效性。

The effectiveness of the pregnancy adapted YEARS algorithm to safely identify patients for CT pulmonary angiogram in pregnant and puerperal patients suspected of having pulmonary embolism.

作者信息

Potgieter Riaan, Becker Piet, Suleman Farhana

机构信息

Department of Diagnostic Radiology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.

Department of Statistics, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.

出版信息

SA J Radiol. 2022 Jul 29;26(1):2454. doi: 10.4102/sajr.v26i1.2454. eCollection 2022.

DOI:10.4102/sajr.v26i1.2454
PMID:35936228
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9350534/
Abstract

BACKGROUND

Pulmonary thromboembolism is one of the leading causes of maternal death worldwide. Globally there has been increasing physician reliance on CT pulmonary angiogram for definitive diagnoses and exclusion of pulmonary thromboembolism. The problem, however, arises when considering the high radiation penalty from performing these investigations, highlighted by the low diagnostic yield. Of recent, the pregnancy-adapted YEARS algorithm has shown promise in international studies as a possible alternative for stratifying risk of pulmonary thromboembolism during the pregnancy and puerperal period.

OBJECTIVES

To determine the effectiveness of the pregnancy adapted YEARS algorithm to safely minimise the number of true negative CT pulmonary angiograms for patients suspected of having pulmonary embolism in our clinical setting.

METHOD

A cross-sectional study was performed in a tertiary hospital in Gauteng on puerperal and pregnant patients suspected of having pulmonary embolism. We retrospectively applied the pregnancy adapted YEARS algorithm and reviewed the various outcomes.

RESULTS

The pregnancy adapted YEARS algorithm proved effective in safely identifying patients for CT pulmonary angiography. By retrospectively applying the algorithm, there could have been a 25.7% scan reduction, whilst maintaining a negative predictive value of 100.0%.

CONCLUSION

As physician reliance on radiological investigations increases, we must remain cognisant of the added radiation exposure and the long-term adverse effects of ionising radiation. The pregnancy-adapted YEARS algorithm provides a safe, reproducible alternative to aid our bid going forward.

摘要

背景

肺血栓栓塞症是全球孕产妇死亡的主要原因之一。在全球范围内,医生越来越依赖CT肺动脉造影来明确诊断和排除肺血栓栓塞症。然而,考虑到进行这些检查会带来高辐射剂量,且诊断率较低,问题随之而来。最近,适用于孕期的YEARS算法在国际研究中显示出有望成为孕期和产褥期肺血栓栓塞症风险分层的一种替代方法。

目的

确定在我们的临床环境中,适用于孕期的YEARS算法对安全减少疑似肺栓塞患者的真阴性CT肺动脉造影检查数量的有效性。

方法

在豪登省的一家三级医院对疑似肺栓塞的产褥期和孕期患者进行了一项横断面研究。我们回顾性应用了适用于孕期的YEARS算法并评估结果。

结果

适用于孕期的YEARS算法被证明在安全识别需要进行CT肺动脉造影的患者方面是有效的。通过回顾性应用该算法,扫描次数可减少25.7%,同时保持100.0%的阴性预测值。

结论

随着医生对放射学检查的依赖增加,我们必须意识到额外的辐射暴露以及电离辐射的长期不良影响。适用于孕期的YEARS算法提供了一种安全、可重复的替代方法,有助于我们未来的工作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7d6/9350534/bcb704e10c12/SAJR-26-2454-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7d6/9350534/7ff6e5df4c84/SAJR-26-2454-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7d6/9350534/79fe8270e9c0/SAJR-26-2454-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7d6/9350534/fddd9ac242ac/SAJR-26-2454-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7d6/9350534/cd05fa02f503/SAJR-26-2454-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7d6/9350534/bcb704e10c12/SAJR-26-2454-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7d6/9350534/7ff6e5df4c84/SAJR-26-2454-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7d6/9350534/79fe8270e9c0/SAJR-26-2454-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7d6/9350534/fddd9ac242ac/SAJR-26-2454-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7d6/9350534/cd05fa02f503/SAJR-26-2454-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7d6/9350534/bcb704e10c12/SAJR-26-2454-g005.jpg

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Pregnancy-Adapted YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism.
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N Engl J Med. 2019 Mar 21;380(12):1139-1149. doi: 10.1056/NEJMoa1813865.
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